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Search Results for " alk-2-in-2 "

8

Compounds

Cat No. Product Name Synonyms Targets
T10287 ALK2-IN-2 ALK , TGF-beta/Smad
ALK2-IN-2 is a potent and selective inhibitor of activin receptor-like kinase 2 (ALK2) (IC50: 9 nM), inhibiting ALK2 700-fold more than ALK3.
T39764 ALK2-IN-4 ALK2-IN-4
ALK2-IN-4, a highly effective ALK2 inhibitor.
T79393 ALK/EGFR-IN-2
ALK/EGFR-IN-2 is a potent dual inhibitor targeting ALK and EGFR, promoting apoptosis and G0/G1 cell cycle arrest in cancer cells. It effectively suppresses proliferation in H1975, PC9, and Baf3-EML4-ALK cancer cell lines...
T40065 ALK2-IN-4 succinate ALK2-IN-4 succinate
ALK2-IN-4 succinate is a robust and effective inhibitor of ALK2.
T3059 ALK-IN-1 AP26113,Brigatinib,AP26113-analog EGFR , IGF-1R , ALK
ALK-IN-1 (AP26113) is a potent ALK inhibitor with IC50 of 0.62 nM in a cell-free assay, demonstrated ability overcome Crizotinib resistance mediated by a L1196M mutation. Phase 2.
T62546 ALK5-IN-27
ALK5-IN-27 (Compound EX-04) is a potent inhibitor of ALK-5 (IC50 ≤ 10 nM). ALK5-IN-27 also inhibits ALK-2.
T62393 ALK5-IN-25
ALK5-IN-25 (compound EX-02) is a potent inhibitor of ALK-5 (IC50<10 nM) and also inhibits ALK-2. ALK5-IN-25 can be used in cancer research.
T13139 TP-008 TGFβRI-IN-2 Others
TGFβRI-IN-2 is a selective, potent and orally active inhibitor of (Activin-Like Kinase 5) ALK 5(pIC50 and pEC50 values of 7.6 and 6.63, respectively).
TargetMol