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Search Results for " adam10 "

6

Compounds

Cat No. Product Name Synonyms Targets
T8961 GW280264X Carbamic acid MMP
GW280264X (Carbamic acid) is an inhibitor of ADAM17 .
T7522 GI254023X GI 254023X MMP , Immunology/Inflammation related
GI254023X is a potent MMP9 and ADAM10 inhibitor (IC50s: 2.5 and 5.3 nM) with 100-fold selectivity for the α-secretase ADAM10 over ADAM17 (TACE). GI254023X can remarkably inhibit the proliferation and induce the apoptosis...
T27603 INCB3619 INCB-3619,INCB 3619 Immunology/Inflammation related
INCB3619 is a selective and potent inhibitor of ADAM with antitumour effects, inhibiting ADAM10, ADAM17, MMP12 and MMP15.
T27654 JG26 JG 26,JG-26 MMP , Immunology/Inflammation related
JG26 is a potent inhibitor of ADAM17, which can inhibit ADAM8, ADAM17, ADAM10 and MMP-12, with IC50 values of 12 nM, 1.9 nM, 150 nM and 9.4 nM, respectively, and can be used to study the immune system of the body.
T40901 Aderbasib INCB007839,INCB7839
Aderbasib (INCB007839) is a highly potent and orally active hydroxamate-based inhibitor of ADAM10 and ADAM17, with low nanomolar affinity. This compound demonstrates strong antineoplastic activity and holds potential for...
T28985 TMI-1 WAY-171318 Apoptosis , MMP
TMI-1 (WAY-171318), a novel orally active inhibitor of ADAM17 (TACE) and MMP, induces tumor apoptosis in a breast cancer.
TargetMol