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Search Results for " acat2 "

8

Compounds

Cat No. Product Name Synonyms Targets
T2753 Avasimibe PD-148515,CI-1011 P450 , Acyltransferase
Avasimibe (PD-148515) is an orally bioavailable inhibitor of acyl-Coenzyme A: cholesterol acyltransferase (ACAT, IC50: 3.3 μM) that prevents cholesterol deposition in the arterial wall. It also inhibits human P450 isoenz...
T31611 Eldacimibe WAY-ACA-147,UNII-4PBL76O2G8,ANA 147,ACA 147 Acyltransferase
Eldacimibe (WAY-ACA-147) is an ACAT2 inhibitor for the treatment of cardiovascular disease and endocrine and metabolic disorders, study of atherosclerosis and hypercholesterolemia.
T12225L Nevanimibe hydrochloride PD-132301 hydrochloride,ATR101 hydrochloride Apoptosis , Acyltransferase
Nevanimibe hydrochloride (PD-132301 hydrochloride) is an orally active and selective inhibitor of acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) (EC50 of 9 nM).
T11733 K-604 dihydrochloride Acyltransferase
K-604 dihydrochloride is a potent and selective acyl-CoA:cholesterol acyltransferase 1 inhibitor with an IC50 of 0.45±0.06 μM.
T12592 Pyripyropene A Others
Pyripyropene A is a potent and selective inhibitor of sterol O-acyltransferase 2 (SOAT2)/acyl-coenzyme A:cholesterol acyltransferase 2 (ACAT2)(IC50 of 0.07 µM).
T62974 Pactimibe sulfate
Pactimibe sulfate (CS-505) is a dual ACAT1/2 inhibitor, acting on ACAT1 (IC50: 4.9 μM) and ACAT2 (IC50: 3.0 μM). Pactimibe sulfate inhibited oleoyl-CoA non-competitively (Ki: 5.6 μM) and significantly inhibited cholester...
T12225 Nevanimibe ATR-101,PD-132301 Others
Nevanimibe is an orally active and selective inhibitor of acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) (EC50 of 9 nM).
T28290 Pactimibe CS 505,CS-505,CS505,Pactimibe free base
Pactimibe is a ACAT inhibitor. It has anti-atherosclerotic activity.
TargetMol