a1ar — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T60687	A1AR antagonist 1
	A1AR antagonist 1 (compound 18g) is a potent antagonist of A1 adenosine receptor (AR). A1AR antagonist 1 has Ki values of 2.08, 6.91, and 31.2 nM for hA1, hA2A and hA2B, respectively [1].
T60580	A1AR antagonist 2
	A1AR antagonist 2 (compound 18h) is a potent antagonist of the A1 adenosine receptor (AR). A1AR antagonist 2 has Ki values of 1.49, 10.2, and 50.1 nM for hA 1, hA 2A, and hA 2B, respectively [1].
T61536	A1AR antagonist 4
	A1AR antagonist 4 (compound 22) is a highly developed chemical compound that acts as a potent and selective antagonist of the A1 adenosine receptor (A1AR). It possesses a pIC50 value of 5.51 and a pKi value of 6.29 [1].
T60615	A1AR antagonist 6
	A1AR antagonist 6 (compound 15) is a potent and selective antagonist of A1 adenosine receptor(A1AR) with a pKi of 7.13 and a pIC 50 of 6.38[1].
T60915	A1AR antagonist 5
	A1AR antagonist 5 (compound 20) is a potent and selective antagonist of A1 adenosine receptor (A1AR) with a pKi of 6.11 and a pIC 50 of 5.83 [1].
T62348	A1AR antagonist 3
	A1AR antagonist 3 (compound 13) is a selective adenylate 1 (A1) receptor antagonist that acts on human A1 (Ki: 9.69 nM) and rat A1 (Ki: 0.529 nM). A1AR antagonist 3 can be used to study neurological diseases.
T12163	N6-(2-Phenylethyl)adenosine	N6-Phenethyladenosine,N6-Phenylethyladenosine	Adenosine Receptor
	N6-(2-Phenylethyl)adenosine (N6-Phenethyladenosine) is an adenosine derivative and an agonist of adenosine receptors with Ki values of 11.8 nM and 30.1 nM for rat and human A1.		Adenosine Receptor
T9330	MIPS521	{2-Amino-4-[3,5-bis(trifluoromethyl)phenyl]thiophen-3-yl}(4-chlorophenyl)methanone	Adenosine Receptor
	MIPS521 ({2-Amino-4-[3,5-bis(trifluoromethyl)phenyl]thiophen-3-yl}(4-chlorophenyl)methanone) is a positive allosteric modulator of the A1R.		Adenosine Receptor
T22489	2'-MeCCPA	2-Chloro-N-cyclopentyl-2′-C-methyladenosine	HCV Protease , Adenosine Receptor
	2'-MeCCPA is a potent and highly selective A1 adenosine receptor (A1AR) agonist with a K-value of 1.8 nM for AR.2'-MeCCPA inhibits trichostatin-stimulated adenylate cyclase activity with an IC value of 13.1 nM.2'-MeCCPA ...		HCV Protease , Adenosine Receptor
T39039	FSCPX		Adenosine Receptor
	FSCPX is a potent and selective irreversible antagonist of the A1 adenosine receptor (A1AR), exhibiting low nanomolar binding potency. Additionally, FSCPX can effectively decrease the interstitial adenosine level in the ...		Adenosine Receptor
T12161	N6-Ethyladenosine		Adenosine Receptor
	N6-Ethyladenosine is an adenosine derivative, acts as an agonist of Adenosine receptor(hA1AR and hA3AR with Kis of 4.9 and 4.7 nM , respectively).		Adenosine Receptor
T31086	CPFPX	[18F]CPFPX
	CPFPX is a highly selective radioactive ligand for the A1 adenosine receptor (A1AR).
T70421	VCP746
	VCP-746 is a potent adenosine A2B receptor agonist that stimulates anti-fibrotic signalling. VCP746 reduces hypertrophy in a rat neonatal cardiac myocyte model. VCP746 is a hybrid molecule consisting of an adenosine moie...
T60732	A2A/A1 AR antagonist-1
	A2A/A1 AR antagonist-1 (compound 1a) has the potential for ischemic stroke research which is potent A 2A /A 1 AR dual antagonist with Ki s of 5.58 and 24.2 nM, respectively [1].
T62018	Adenosine receptor inhibitor 2
	Adenosine receptor inhibitor 2 (compound 14b) is a potent inhibitor of AR (adenosine receptor). Adenosine receptor inhibitor 2 exhibits dual affinity toward A 1 /A 2A ARs with higher affinity for the A 1 - than the A 2A ...