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Search Results for " 5t4 "

3

Compounds

12

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T12081 MMAF-OMe Monomethyl auristatin F methyl ester
MMAF-OMe (Monomethyl auristatin F methyl ester) is an antitubulin agent which inhibits several tumor cell lines with IC50s of 0.056 nM, 0.166 nM, 0.183 nM, and 0.449 nM for MDAMB435/5T4, MDAMB361DYT2, MDAMB468, and Raji ...
T74880 Cys-McMMAF
Cys-McMMAF, the active compound liberated from AlMcMMAF—a humanized anti-5T4 A1 antibody connected to the microtubule-disrupting molecule MMAF through a maleimidocaproyl linker—demonstrates antitumor effectiveness in two...
T83121 Anatumomab mafenatox ABR-214936
Anatumomab mafenatox (ABR-214936), a 73 KDa recombinant protein, targets the tumor-associated antigen 5T4 commonly expressed in malignancies. It is a conjugate comprising a modified form of SEA linked to a murine Fab. Th...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-05033 5T4/TPBG Protein, Human, Recombinant (aa 60-345, His) Human HEK293 Cells
Trophoblast glycoprotein (TPBG), also known as 5T4, is the therapeutic target of several anticancer agents currently in clinical development, largely due to its high expression in tumors and low expression in normal adul...
TMPJ-00269 5T4/TPBG Protein, Human, Recombinant (mFc) Human HEK293 Cells
5T4/TPBG Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 80-110 KDa and the accession number is Q13641.
TMPJ-01153 5T4/TPBG Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293 Cells
5T4/TPBG Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 55-80 KDa and the accession number is Q4R8Y9.
TMPJ-00268 5T4/TPBG Protein, Human, Recombinant (Avi & His), Biotinylated Human HEK293 Cells
5T4/TPBG Protein, Human, Recombinant (Avi & His), Biotinylated is expressed in HEK293 mammalian cells with C-Avi-6xHis tag. The predicted molecular weight is 60-90 KDa and the accession number is Q13641.
TMPK-00270 TPBG/5T4 Protein, Human, Recombinant (His & Avi), FITC-Labeled Human HEK293 Cells
The oncofetal tumor-associated antigen 5T4 (TBGP) has been linked with CSC properties in several different malignancies. 5T4 has functional attributes that are relevant to the spread of tumors including through EMT, CXCR...
TMPK-00271 TPBG/5T4 Protein, Human, Recombinant (His & Avi) Human HEK293 Cells
The oncofetal tumor-associated antigen 5T4 (TBGP) has been linked with CSC properties in several different malignancies. 5T4 has functional attributes that are relevant to the spread of tumors including through EMT, CXCR...
TMPY-06214 5T4/TPBG Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
Trophoblast glycoprotein (TPBG), also known as 5T4, is the therapeutic target of several anticancer agents currently in clinical development, largely due to its high expression in tumors and low expression in normal adul...
TMPY-06191 5T4/TPBG Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Trophoblast glycoprotein (TPBG), also known as 5T4, is the therapeutic target of several anticancer agents currently in clinical development, largely due to its high expression in tumors and low expression in normal adul...
TMPH-02437 5T4/TPBG Protein, Cynomolgus, Recombinant (His & Myc) Cynomolgus HEK293 Cells
May function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization. 5T4/TPBG Protein, Cynomolgus, Recombinant (His & Myc) is expressed in HEK2...
TMPH-03392 5T4/TPBG Protein, Rat, Recombinant (His & SUMO) Rat E. coli
May function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization. 5T4/TPBG Protein, Rat, Recombinant (His & SUMO) is expressed in E. coli ex...
TMPY-06317 5T4/TPBG Protein, Human, Recombinant (aa 1-355, His) Human HEK293 Cells
Trophoblast glycoprotein (TPBG), also known as 5T4, is the therapeutic target of several anticancer agents currently in clinical development, largely due to its high expression in tumors and low expression in normal adul...
TMPH-02436 5T4/TPBG Protein, Cynomolgus, Recombinant (E. coli, His & Myc) Cynomolgus E. coli
May function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization. 5T4/TPBG Protein, Cynomolgus, Recombinant (E. coli, His & Myc) is expresse...
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