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Cat No. | Product Name | Synonyms | Targets |
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T12081 | MMAF-OMe | Monomethyl auristatin F methyl ester | |
MMAF-OMe (Monomethyl auristatin F methyl ester) is an antitubulin agent which inhibits several tumor cell lines with IC50s of 0.056 nM, 0.166 nM, 0.183 nM, and 0.449 nM for MDAMB435/5T4, MDAMB361DYT2, MDAMB468, and Raji ... | |||
T74880 | Cys-McMMAF | ||
Cys-McMMAF, the active compound liberated from AlMcMMAF—a humanized anti-5T4 A1 antibody connected to the microtubule-disrupting molecule MMAF through a maleimidocaproyl linker—demonstrates antitumor effectiveness in two... | |||
T83121 | Anatumomab mafenatox | ABR-214936 | |
Anatumomab mafenatox (ABR-214936), a 73 KDa recombinant protein, targets the tumor-associated antigen 5T4 commonly expressed in malignancies. It is a conjugate comprising a modified form of SEA linked to a murine Fab. Th... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-05033 | 5T4/TPBG Protein, Human, Recombinant (aa 60-345, His) | Human | HEK293 Cells |
Trophoblast glycoprotein (TPBG), also known as 5T4, is the therapeutic target of several anticancer agents currently in clinical development, largely due to its high expression in tumors and low expression in normal adul... | |||
TMPJ-00269 | 5T4/TPBG Protein, Human, Recombinant (mFc) | Human | HEK293 Cells |
5T4/TPBG Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 80-110 KDa and the accession number is Q13641. | |||
TMPJ-01153 | 5T4/TPBG Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
5T4/TPBG Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 55-80 KDa and the accession number is Q4R8Y9. | |||
TMPJ-00268 | 5T4/TPBG Protein, Human, Recombinant (Avi & His), Biotinylated | Human | HEK293 Cells |
5T4/TPBG Protein, Human, Recombinant (Avi & His), Biotinylated is expressed in HEK293 mammalian cells with C-Avi-6xHis tag. The predicted molecular weight is 60-90 KDa and the accession number is Q13641. | |||
TMPK-00270 | TPBG/5T4 Protein, Human, Recombinant (His & Avi), FITC-Labeled | Human | HEK293 Cells |
The oncofetal tumor-associated antigen 5T4 (TBGP) has been linked with CSC properties in several different malignancies. 5T4 has functional attributes that are relevant to the spread of tumors including through EMT, CXCR... | |||
TMPK-00271 | TPBG/5T4 Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
The oncofetal tumor-associated antigen 5T4 (TBGP) has been linked with CSC properties in several different malignancies. 5T4 has functional attributes that are relevant to the spread of tumors including through EMT, CXCR... | |||
TMPY-06214 | 5T4/TPBG Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
Trophoblast glycoprotein (TPBG), also known as 5T4, is the therapeutic target of several anticancer agents currently in clinical development, largely due to its high expression in tumors and low expression in normal adul... | |||
TMPY-06191 | 5T4/TPBG Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Trophoblast glycoprotein (TPBG), also known as 5T4, is the therapeutic target of several anticancer agents currently in clinical development, largely due to its high expression in tumors and low expression in normal adul... | |||
TMPH-02437 | 5T4/TPBG Protein, Cynomolgus, Recombinant (His & Myc) | Cynomolgus | HEK293 Cells |
May function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization. 5T4/TPBG Protein, Cynomolgus, Recombinant (His & Myc) is expressed in HEK2... | |||
TMPH-03392 | 5T4/TPBG Protein, Rat, Recombinant (His & SUMO) | Rat | E. coli |
May function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization. 5T4/TPBG Protein, Rat, Recombinant (His & SUMO) is expressed in E. coli ex... | |||
TMPY-06317 | 5T4/TPBG Protein, Human, Recombinant (aa 1-355, His) | Human | HEK293 Cells |
Trophoblast glycoprotein (TPBG), also known as 5T4, is the therapeutic target of several anticancer agents currently in clinical development, largely due to its high expression in tumors and low expression in normal adul... | |||
TMPH-02436 | 5T4/TPBG Protein, Cynomolgus, Recombinant (E. coli, His & Myc) | Cynomolgus | E. coli |
May function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization. 5T4/TPBG Protein, Cynomolgus, Recombinant (E. coli, His & Myc) is expresse... |