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Platelet-Derived Growth Factors, PDGFs

Platelet-derived growth factor (PDGF) is one among numerous growth factors that regulate cell growth and division. In particular, PDGF plays an important role in blood vessel formation, blood vessel growth in existing vascular tissues, mitosis of mesenchymal cells, and chemotaxis of mesenchymal cells. Platelet-derived growth factor is a dimeric glycoprotein that can be composed of two A subunits (PDGF-AA), two B subunits (PDGF-BB), or one of each (PDGF-AB). There are five different isoforms of PDGF that activate cellular response through two different receptors. Known ligands include: PDGF-AA (PDGFA), -BB (PDGFB), -CC (PDGFC), and -DD (PDGFD), and -AB (a PDGFA and PDGFB heterodimer). The ligands interact with the two tyrosine kinase receptor monomers, PDGFRα (PDGFRA) and -Rβ (PDGFRB). Recombinant PDGF is used in medicine to help heal chronic ulcers and in orthopedic surgery and periodontics as an alternative to bone autograft to stimulate bone regeneration and repair.

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Species
Canine (3)
Cynomolgus (3)
Human (7)
Mouse (5)
Rat (1)
Rhesus (1)
Expression System
Baculovirus Insect Cells (1)
E. coli (4)
HEK293 Cells (6)
P. pastoris (Yeast) (9)
Tag
C-6xHis (1)
C-His (1)
N-6xHis (1)
N-His (10)
N-hFc (4)
N-mFc (1)
Tag Free (2)
Cat No. product name / Synonyms Species Expression System
TMPJ-00767 PDGF-AA Protein, Human, Recombinant
PDGF-AA Protein, Human, Recombinant
Human E. coli
PDGF-AA Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 16 KDa and the accession number is P04085.
TMPJ-00768 PDGF-AA Protein, Human, Recombinant (His)
PDGF-AA Protein, Human, Recombinant (His)
Human E. coli
PDGF-AA Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 16 KDa and the accession ...
TMPK-01178 PDGFD Protein, Cynomolgus, Recombinant (His)
PDGFD Protein, Cynomolgus, Recombinant (His)
Cynomolgus HEK293 Cells
Platelet‑derived growth factor D (PDGF‑D) is a new member of the PDGF family that binds the PDGFR‑β homodimer. PDGF‑D promotes the angiogenic capacity of EPCs, i...
TMPY-00269 PDGFC Protein, Cynomolgus, Recombinant (hFc)
PDGFC Protein, Cynomolgus, Recombinant (hFc)
Cynomolgus HEK293 Cells
PDGFC Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40.9 kDa and the accession nu...
TMPY-00455 PDGFA Protein, Canine, Recombinant (hFc)
PDGFA Protein, Canine, Recombinant (hFc)
Canine HEK293 Cells
Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progress...
TMPY-00898 PDGFC Protein, Human, Recombinant (hFc)
PDGFC Protein, Human, Recombinant (hFc)
Human HEK293 Cells
PDGFC Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39 kDa and the accession number is...
TMPY-02251 PDGFC Protein, Mouse, Recombinant (hFc)
PDGFC Protein, Mouse, Recombinant (hFc)
Mouse HEK293 Cells
PDGFC Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40.9 kDa and the accession number ...
TMPY-02395 PDGFB Protein, Cynomolgus, Recombinant (mFc)
PDGFB Protein, Cynomolgus, Recombinant (mFc)
Cynomolgus HEK293 Cells
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by in...
TMPY-02815 PDGFC Protein, Human, Recombinant (His)
PDGFC Protein, Human, Recombinant (His)
Human Baculovirus Insect Cells
PDGFC Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 13.89 kDa and the accession numb...
TMPY-04838 PDGFA Protein, Mouse, Recombinant (His)
PDGFA Protein, Mouse, Recombinant (His)
Mouse P. pastoris (Yeast)
Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progress...
TMPY-04877 PDGFB Protein, Mouse, Recombinant (His)
PDGFB Protein, Mouse, Recombinant (His)
Mouse P. pastoris (Yeast)
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by in...
TMPY-05056 PDGFA Protein, Human, Recombinant (His)
PDGFA Protein, Human, Recombinant (His)
Human P. pastoris (Yeast)
Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progress...
TMPY-05068 PDGFA Protein, Rat, Recombinant (His)
PDGFA Protein, Rat, Recombinant (His)
Rat P. pastoris (Yeast)
Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progress...
TMPY-05075 PDGFA Protein, Canine, Recombinant (His)
PDGFA Protein, Canine, Recombinant (His)
Canine P. pastoris (Yeast)
Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progress...
TMPY-05076 PDGFB Protein, Canine, Recombinant (His)
PDGFB Protein, Canine, Recombinant (His)
Canine P. pastoris (Yeast)
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by in...
TMPY-05077 PDGFB Protein, Rhesus, Recombinant (His)
PDGFB Protein, Rhesus, Recombinant (His)
Rhesus P. pastoris (Yeast)
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by in...
TMPY-04976 PDGFC Protein, Mouse, Recombinant (His)
PDGFC Protein, Mouse, Recombinant (His)
Mouse P. pastoris (Yeast)
PDGFC Protein, Mouse, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 14.4 kDa and the accession number is Q8CI19.
TMPY-04644 PDGFB Protein, Human, Recombinant (His)
PDGFB Protein, Human, Recombinant (His)
Human P. pastoris (Yeast)
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by in...
TMPJ-00562 PDGF-BB Protein, Mouse, Recombinant (His)
PDGF-BB Protein, Mouse, Recombinant (His)
Mouse E. coli
Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of m...
TMPJ-00735 PDGF-BB Protein, Human, Recombinant
PDGF-BB Protein, Human, Recombinant
Human E. coli
Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of m...
PDGF-AA Protein, Human, Recombinant
TMPJ-00767
PDGF-AA Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 16 KDa and the accession number is P04085.
PDGF-AA Protein, Human, Recombinant (His)
TMPJ-00768
PDGF-AA Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 16 KDa and the accession ...
PDGFD Protein, Cynomolgus, Recombinant (His)
TMPK-01178
Platelet‑derived growth factor D (PDGF‑D) is a new member of the PDGF family that binds the PDGFR‑β homodimer. PDGF‑D promotes the angiogenic capacity of EPCs, i...
PDGFC Protein, Cynomolgus, Recombinant (hFc)
TMPY-00269
PDGFC Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40.9 kDa and the accession nu...
PDGFA Protein, Canine, Recombinant (hFc)
TMPY-00455
Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progress...
PDGFC Protein, Human, Recombinant (hFc)
TMPY-00898
PDGFC Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39 kDa and the accession number is...
PDGFC Protein, Mouse, Recombinant (hFc)
TMPY-02251
PDGFC Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40.9 kDa and the accession number ...
PDGFB Protein, Cynomolgus, Recombinant (mFc)
TMPY-02395
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by in...
PDGFC Protein, Human, Recombinant (His)
TMPY-02815
PDGFC Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 13.89 kDa and the accession numb...
PDGFA Protein, Mouse, Recombinant (His)
TMPY-04838
Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progress...
PDGFB Protein, Mouse, Recombinant (His)
TMPY-04877
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by in...
PDGFA Protein, Human, Recombinant (His)
TMPY-05056
Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progress...
PDGFA Protein, Rat, Recombinant (His)
TMPY-05068
Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progress...
PDGFA Protein, Canine, Recombinant (His)
TMPY-05075
Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progress...
PDGFB Protein, Canine, Recombinant (His)
TMPY-05076
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by in...
PDGFB Protein, Rhesus, Recombinant (His)
TMPY-05077
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by in...
PDGFC Protein, Mouse, Recombinant (His)
TMPY-04976
PDGFC Protein, Mouse, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 14.4 kDa and the accession number is Q8CI19.
PDGFB Protein, Human, Recombinant (His)
TMPY-04644
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by in...
PDGF-BB Protein, Mouse, Recombinant (His)
TMPJ-00562
Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of m...
PDGF-BB Protein, Human, Recombinant
TMPJ-00735
Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of m...
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TargetMol