Platelet-derived growth factor (PDGF) is one among numerous growth factors that regulate cell growth and division. In particular, PDGF plays an important role in blood vessel formation, blood vessel growth in existing vascular tissues, mitosis of mesenchymal cells, and chemotaxis of mesenchymal cells. Platelet-derived growth factor is a dimeric glycoprotein that can be composed of two A subunits (PDGF-AA), two B subunits (PDGF-BB), or one of each (PDGF-AB). There are five different isoforms of PDGF that activate cellular response through two different receptors. Known ligands include: PDGF-AA (PDGFA), -BB (PDGFB), -CC (PDGFC), and -DD (PDGFD), and -AB (a PDGFA and PDGFB heterodimer). The ligands interact with the two tyrosine kinase receptor monomers, PDGFRα (PDGFRA) and -Rβ (PDGFRB). Recombinant PDGF is used in medicine to help heal chronic ulcers and in orthopedic surgery and periodontics as an alternative to bone autograft to stimulate bone regeneration and repair.
Cat No. | product name / Synonyms | Species | Expression System |
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TMPJ-00767 | PDGF-AA Protein, Human, Recombinant
PDGF-AA Protein, Human, Recombinant
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Human | E. coli |
PDGF-AA Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 16 KDa and the accession number is P04085. | |||
TMPJ-00768 | PDGF-AA Protein, Human, Recombinant (His)
PDGF-AA Protein, Human, Recombinant (His)
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Human | E. coli |
PDGF-AA Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 16 KDa and the accession ... | |||
TMPK-01178 | PDGFD Protein, Cynomolgus, Recombinant (His)
PDGFD Protein, Cynomolgus, Recombinant (His)
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Cynomolgus | HEK293 Cells |
Platelet‑derived growth factor D (PDGF‑D) is a new member of the PDGF family that binds the PDGFR‑β homodimer. PDGF‑D promotes the angiogenic capacity of EPCs, i... | |||
TMPY-00269 | PDGFC Protein, Cynomolgus, Recombinant (hFc)
PDGFC Protein, Cynomolgus, Recombinant (hFc)
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Cynomolgus | HEK293 Cells |
PDGFC Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40.9 kDa and the accession nu... | |||
TMPY-00455 | PDGFA Protein, Canine, Recombinant (hFc)
PDGFA Protein, Canine, Recombinant (hFc)
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Canine | HEK293 Cells |
Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progress... | |||
TMPY-00898 | PDGFC Protein, Human, Recombinant (hFc)
PDGFC Protein, Human, Recombinant (hFc)
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Human | HEK293 Cells |
PDGFC Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39 kDa and the accession number is... | |||
TMPY-02251 | PDGFC Protein, Mouse, Recombinant (hFc)
PDGFC Protein, Mouse, Recombinant (hFc)
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Mouse | HEK293 Cells |
PDGFC Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40.9 kDa and the accession number ... | |||
TMPY-02395 | PDGFB Protein, Cynomolgus, Recombinant (mFc)
PDGFB Protein, Cynomolgus, Recombinant (mFc)
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Cynomolgus | HEK293 Cells |
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by in... | |||
TMPY-02815 | PDGFC Protein, Human, Recombinant (His)
PDGFC Protein, Human, Recombinant (His)
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Human | Baculovirus Insect Cells |
PDGFC Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 13.89 kDa and the accession numb... | |||
TMPY-04838 | PDGFA Protein, Mouse, Recombinant (His)
PDGFA Protein, Mouse, Recombinant (His)
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Mouse | P. pastoris (Yeast) |
Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progress... | |||
TMPY-04877 | PDGFB Protein, Mouse, Recombinant (His)
PDGFB Protein, Mouse, Recombinant (His)
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Mouse | P. pastoris (Yeast) |
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by in... | |||
TMPY-05056 | PDGFA Protein, Human, Recombinant (His)
PDGFA Protein, Human, Recombinant (His)
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Human | P. pastoris (Yeast) |
Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progress... | |||
TMPY-05068 | PDGFA Protein, Rat, Recombinant (His)
PDGFA Protein, Rat, Recombinant (His)
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Rat | P. pastoris (Yeast) |
Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progress... | |||
TMPY-05075 | PDGFA Protein, Canine, Recombinant (His)
PDGFA Protein, Canine, Recombinant (His)
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Canine | P. pastoris (Yeast) |
Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progress... | |||
TMPY-05076 | PDGFB Protein, Canine, Recombinant (His)
PDGFB Protein, Canine, Recombinant (His)
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Canine | P. pastoris (Yeast) |
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by in... | |||
TMPY-05077 | PDGFB Protein, Rhesus, Recombinant (His)
PDGFB Protein, Rhesus, Recombinant (His)
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Rhesus | P. pastoris (Yeast) |
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by in... | |||
TMPY-04976 | PDGFC Protein, Mouse, Recombinant (His)
PDGFC Protein, Mouse, Recombinant (His)
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Mouse | P. pastoris (Yeast) |
PDGFC Protein, Mouse, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 14.4 kDa and the accession number is Q8CI19. | |||
TMPY-04644 | PDGFB Protein, Human, Recombinant (His)
PDGFB Protein, Human, Recombinant (His)
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Human | P. pastoris (Yeast) |
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by in... | |||
TMPJ-00562 | PDGF-BB Protein, Mouse, Recombinant (His)
PDGF-BB Protein, Mouse, Recombinant (His)
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Mouse | E. coli |
Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of m... | |||
TMPJ-00735 | PDGF-BB Protein, Human, Recombinant
PDGF-BB Protein, Human, Recombinant
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Human | E. coli |
Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of m... |