Home Tools
Log in
Cart

Platelet-Derived Growth Factors, PDGFs

Platelet-derived growth factor (PDGF) is one among numerous growth factors that regulate cell growth and division. In particular, PDGF plays an important role in blood vessel formation, blood vessel growth in existing vascular tissues, mitosis of mesenchymal cells, and chemotaxis of mesenchymal cells. Platelet-derived growth factor is a dimeric glycoprotein that can be composed of two A subunits (PDGF-AA), two B subunits (PDGF-BB), or one of each (PDGF-AB). There are five different isoforms of PDGF that activate cellular response through two different receptors. Known ligands include: PDGF-AA (PDGFA), -BB (PDGFB), -CC (PDGFC), and -DD (PDGFD), and -AB (a PDGFA and PDGFB heterodimer). The ligands interact with the two tyrosine kinase receptor monomers, PDGFRα (PDGFRA) and -Rβ (PDGFRB). Recombinant PDGF is used in medicine to help heal chronic ulcers and in orthopedic surgery and periodontics as an alternative to bone autograft to stimulate bone regeneration and repair.

1
Species
Canine (3)
Cynomolgus (3)
Human (7)
Mouse (5)
Rat (1)
Rhesus (1)
Expression System
Baculovirus-Insect Cells (1)
E. coli (4)
HEK293 (6)
Yeast (9)
Tag
C-6His (1)
His (10)
N-6His (1)
N-His (1)
None (2)
hFc (4)
mFc (1)
Cat No. product name / Synonyms Species Expression System
TMPJ-00767 PDGF-AA Protein, Human, Recombinant
PDGF-AA Protein, Human, Recombinant
Human E. coli
Platelet-derived growth factor subunit A (PDGFA), belongs to the PDGF/VEGF growth factor family. PDGFA is a secreted protein, stored in platelet alpha-granules a...
TMPJ-00768 PDGF-AA Protein, Human, Recombinant (His)
PDGF-AA Protein, Human, Recombinant (His)
Human E. coli
Platelet-derived growth factor subunit A (PDGFA), belongs to the PDGF/VEGF growth factor family. PDGFA is a secreted protein, stored in platelet alpha-granules a...
TMPK-01178 PDGFD Protein, Cynomolgus, Recombinant (His)
PDGFD Protein, Cynomolgus, Recombinant (His)
Cynomolgus HEK293
Platelet‑derived growth factor D (PDGF‑D) is a new member of the PDGF family that binds the PDGFR‑β homodimer. PDGF‑D promotes the angiogenic capacity of EPCs, i...
TMPY-00269 PDGFC Protein, Cynomolgus, Recombinant (hFc)
PDGFC Protein, Cynomolgus, Recombinant (hFc)
Cynomolgus HEK293
PDGF-C is a member of the PDGF/VEGF family of growth factors with a unique domain organization and expression pattern. Platelet-derived growth factor receptors (...
TMPY-00455 PDGFA Protein, Canine, Recombinant (hFc)
PDGFA Protein, Canine, Recombinant (hFc)
Canine HEK293
Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progress...
TMPY-00898 PDGFC Protein, Human, Recombinant (hFc)
PDGFC Protein, Human, Recombinant (hFc)
Human HEK293
PDGF-C is a member of the PDGF/VEGF family of growth factors with a unique domain organization and expression pattern. Platelet-derived growth factor receptors (...
TMPY-02251 PDGFC Protein, Mouse, Recombinant (hFc)
PDGFC Protein, Mouse, Recombinant (hFc)
Mouse HEK293
PDGF-C is a member of the PDGF/VEGF family of growth factors with a unique domain organization and expression pattern. Platelet-derived growth factor receptors (...
TMPY-02395 PDGFB Protein, Cynomolgus, Recombinant (mFc)
PDGFB Protein, Cynomolgus, Recombinant (mFc)
Cynomolgus HEK293
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by in...
TMPY-02815 PDGFC Protein, Human, Recombinant (His)
PDGFC Protein, Human, Recombinant (His)
Human Baculovirus-Insect Cells
PDGF-C is a member of the PDGF/VEGF family of growth factors with a unique domain organization and expression pattern. Platelet-derived growth factor receptors (...
TMPY-04838 PDGFA Protein, Mouse, Recombinant (His)
PDGFA Protein, Mouse, Recombinant (His)
Mouse Yeast
Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progress...
TMPY-04877 PDGFB Protein, Mouse, Recombinant (His)
PDGFB Protein, Mouse, Recombinant (His)
Mouse Yeast
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by in...
TMPY-05056 PDGFA Protein, Human, Recombinant (His)
PDGFA Protein, Human, Recombinant (His)
Human Yeast
Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progress...
TMPY-05068 PDGFA Protein, Rat, Recombinant (His)
PDGFA Protein, Rat, Recombinant (His)
Rat Yeast
Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progress...
TMPY-05075 PDGFA Protein, Canine, Recombinant (His)
PDGFA Protein, Canine, Recombinant (His)
Canine Yeast
Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progress...
TMPY-05076 PDGFB Protein, Canine, Recombinant (His)
PDGFB Protein, Canine, Recombinant (His)
Canine Yeast
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by in...
TMPY-05077 PDGFB Protein, Rhesus, Recombinant (His)
PDGFB Protein, Rhesus, Recombinant (His)
Rhesus Yeast
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by in...
TMPY-04976 PDGFC Protein, Mouse, Recombinant (His)
PDGFC Protein, Mouse, Recombinant (His)
Mouse Yeast
PDGF-C is a member of the PDGF/VEGF family of growth factors with a unique domain organization and expression pattern. Platelet-derived growth factor receptors (...
TMPY-04644 PDGFB Protein, Human, Recombinant (His)
PDGFB Protein, Human, Recombinant (His)
Human Yeast
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by in...
TMPJ-00562 PDGF-BB Protein, Mouse, Recombinant (His)
PDGF-BB Protein, Mouse, Recombinant (His)
Mouse E. coli
Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of m...
TMPJ-00735 PDGF-BB Protein, Human, Recombinant
PDGF-BB Protein, Human, Recombinant
Human E. coli
Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of m...
PDGF-AA Protein, Human, Recombinant
TMPJ-00767
Platelet-derived growth factor subunit A (PDGFA), belongs to the PDGF/VEGF growth factor family. PDGFA is a secreted protein, stored in platelet alpha-granules a...
PDGF-AA Protein, Human, Recombinant (His)
TMPJ-00768
Platelet-derived growth factor subunit A (PDGFA), belongs to the PDGF/VEGF growth factor family. PDGFA is a secreted protein, stored in platelet alpha-granules a...
PDGFD Protein, Cynomolgus, Recombinant (His)
TMPK-01178
Platelet‑derived growth factor D (PDGF‑D) is a new member of the PDGF family that binds the PDGFR‑β homodimer. PDGF‑D promotes the angiogenic capacity of EPCs, i...
PDGFC Protein, Cynomolgus, Recombinant (hFc)
TMPY-00269
PDGF-C is a member of the PDGF/VEGF family of growth factors with a unique domain organization and expression pattern. Platelet-derived growth factor receptors (...
PDGFA Protein, Canine, Recombinant (hFc)
TMPY-00455
Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progress...
PDGFC Protein, Human, Recombinant (hFc)
TMPY-00898
PDGF-C is a member of the PDGF/VEGF family of growth factors with a unique domain organization and expression pattern. Platelet-derived growth factor receptors (...
PDGFC Protein, Mouse, Recombinant (hFc)
TMPY-02251
PDGF-C is a member of the PDGF/VEGF family of growth factors with a unique domain organization and expression pattern. Platelet-derived growth factor receptors (...
PDGFB Protein, Cynomolgus, Recombinant (mFc)
TMPY-02395
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by in...
PDGFC Protein, Human, Recombinant (His)
TMPY-02815
PDGF-C is a member of the PDGF/VEGF family of growth factors with a unique domain organization and expression pattern. Platelet-derived growth factor receptors (...
PDGFA Protein, Mouse, Recombinant (His)
TMPY-04838
Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progress...
PDGFB Protein, Mouse, Recombinant (His)
TMPY-04877
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by in...
PDGFA Protein, Human, Recombinant (His)
TMPY-05056
Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progress...
PDGFA Protein, Rat, Recombinant (His)
TMPY-05068
Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progress...
PDGFA Protein, Canine, Recombinant (His)
TMPY-05075
Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progress...
PDGFB Protein, Canine, Recombinant (His)
TMPY-05076
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by in...
PDGFB Protein, Rhesus, Recombinant (His)
TMPY-05077
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by in...
PDGFC Protein, Mouse, Recombinant (His)
TMPY-04976
PDGF-C is a member of the PDGF/VEGF family of growth factors with a unique domain organization and expression pattern. Platelet-derived growth factor receptors (...
PDGFB Protein, Human, Recombinant (His)
TMPY-04644
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by in...
PDGF-BB Protein, Mouse, Recombinant (His)
TMPJ-00562
Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of m...
PDGF-BB Protein, Human, Recombinant
TMPJ-00735
Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of m...
1
TargetMol