Platelet-derived growth factor (PDGF) is one among numerous growth factors that regulate cell growth and division. In particular, PDGF plays an important role in blood vessel formation, blood vessel growth in existing vascular tissues, mitosis of mesenchymal cells, and chemotaxis of mesenchymal cells. Platelet-derived growth factor is a dimeric glycoprotein that can be composed of two A subunits (PDGF-AA), two B subunits (PDGF-BB), or one of each (PDGF-AB). There are five different isoforms of PDGF that activate cellular response through two different receptors. Known ligands include: PDGF-AA (PDGFA), -BB (PDGFB), -CC (PDGFC), and -DD (PDGFD), and -AB (a PDGFA and PDGFB heterodimer). The ligands interact with the two tyrosine kinase receptor monomers, PDGFRα (PDGFRA) and -Rβ (PDGFRB). Recombinant PDGF is used in medicine to help heal chronic ulcers and in orthopedic surgery and periodontics as an alternative to bone autograft to stimulate bone regeneration and repair.
Cat No. | product name / Synonyms | Species | Expression System |
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TMPJ-00767 | PDGF-AA Protein, Human, Recombinant
PDGF-AA Protein, Human, Recombinant
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Human | E. coli |
Platelet-derived growth factor subunit A (PDGFA), belongs to the PDGF/VEGF growth factor family. PDGFA is a secreted protein, stored in platelet alpha-granules a... | |||
TMPJ-00768 | PDGF-AA Protein, Human, Recombinant (His)
PDGF-AA Protein, Human, Recombinant (His)
|
Human | E. coli |
Platelet-derived growth factor subunit A (PDGFA), belongs to the PDGF/VEGF growth factor family. PDGFA is a secreted protein, stored in platelet alpha-granules a... | |||
TMPK-01178 | PDGFD Protein, Cynomolgus, Recombinant (His)
PDGFD Protein, Cynomolgus, Recombinant (His)
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Cynomolgus | HEK293 |
Platelet‑derived growth factor D (PDGF‑D) is a new member of the PDGF family that binds the PDGFR‑β homodimer. PDGF‑D promotes the angiogenic capacity of EPCs, i... | |||
TMPY-00269 | PDGFC Protein, Cynomolgus, Recombinant (hFc)
PDGFC Protein, Cynomolgus, Recombinant (hFc)
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Cynomolgus | HEK293 |
PDGF-C is a member of the PDGF/VEGF family of growth factors with a unique domain organization and expression pattern. Platelet-derived growth factor receptors (... | |||
TMPY-00455 | PDGFA Protein, Canine, Recombinant (hFc)
PDGFA Protein, Canine, Recombinant (hFc)
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Canine | HEK293 |
Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progress... | |||
TMPY-00898 | PDGFC Protein, Human, Recombinant (hFc)
PDGFC Protein, Human, Recombinant (hFc)
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Human | HEK293 |
PDGF-C is a member of the PDGF/VEGF family of growth factors with a unique domain organization and expression pattern. Platelet-derived growth factor receptors (... | |||
TMPY-02251 | PDGFC Protein, Mouse, Recombinant (hFc)
PDGFC Protein, Mouse, Recombinant (hFc)
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Mouse | HEK293 |
PDGF-C is a member of the PDGF/VEGF family of growth factors with a unique domain organization and expression pattern. Platelet-derived growth factor receptors (... | |||
TMPY-02395 | PDGFB Protein, Cynomolgus, Recombinant (mFc)
PDGFB Protein, Cynomolgus, Recombinant (mFc)
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Cynomolgus | HEK293 |
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by in... | |||
TMPY-02815 | PDGFC Protein, Human, Recombinant (His)
PDGFC Protein, Human, Recombinant (His)
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Human | Baculovirus-Insect Cells |
PDGF-C is a member of the PDGF/VEGF family of growth factors with a unique domain organization and expression pattern. Platelet-derived growth factor receptors (... | |||
TMPY-04838 | PDGFA Protein, Mouse, Recombinant (His)
PDGFA Protein, Mouse, Recombinant (His)
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Mouse | Yeast |
Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progress... | |||
TMPY-04877 | PDGFB Protein, Mouse, Recombinant (His)
PDGFB Protein, Mouse, Recombinant (His)
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Mouse | Yeast |
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by in... | |||
TMPY-05056 | PDGFA Protein, Human, Recombinant (His)
PDGFA Protein, Human, Recombinant (His)
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Human | Yeast |
Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progress... | |||
TMPY-05068 | PDGFA Protein, Rat, Recombinant (His)
PDGFA Protein, Rat, Recombinant (His)
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Rat | Yeast |
Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progress... | |||
TMPY-05075 | PDGFA Protein, Canine, Recombinant (His)
PDGFA Protein, Canine, Recombinant (His)
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Canine | Yeast |
Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progress... | |||
TMPY-05076 | PDGFB Protein, Canine, Recombinant (His)
PDGFB Protein, Canine, Recombinant (His)
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Canine | Yeast |
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by in... | |||
TMPY-05077 | PDGFB Protein, Rhesus, Recombinant (His)
PDGFB Protein, Rhesus, Recombinant (His)
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Rhesus | Yeast |
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by in... | |||
TMPY-04976 | PDGFC Protein, Mouse, Recombinant (His)
PDGFC Protein, Mouse, Recombinant (His)
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Mouse | Yeast |
PDGF-C is a member of the PDGF/VEGF family of growth factors with a unique domain organization and expression pattern. Platelet-derived growth factor receptors (... | |||
TMPY-04644 | PDGFB Protein, Human, Recombinant (His)
PDGFB Protein, Human, Recombinant (His)
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Human | Yeast |
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by in... | |||
TMPJ-00562 | PDGF-BB Protein, Mouse, Recombinant (His)
PDGF-BB Protein, Mouse, Recombinant (His)
|
Mouse | E. coli |
Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of m... | |||
TMPJ-00735 | PDGF-BB Protein, Human, Recombinant
PDGF-BB Protein, Human, Recombinant
|
Human | E. coli |
Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of m... |