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Insulin-like Growth Factors, IGFs

The insulin-like growth factors (IGFs) are proteins with high sequence similarity to insulin. IGFs are part of a complex system that cells use to communicate with their physiologic environment. This complex system (often referred to as the IGF "axis") consists of two cell-surface receptors (IGF1R and IGF2R), two ligands (IGF-1 and IGF-2), a family of seven high-affinity IGF-binding proteins (IGFBP1 to IGFBP7), as well as associated IGFBP degrading enzymes, referred to collectively as proteases. The IGF "axis" is also commonly referred to as the Growth Hormone/IGF-1 Axis. Insulin-like growth factor 1 (IGF-1) is mainly secreted by the liver as a result of stimulation by growth hormone (GH). IGF-1 is important for both the regulation of normal physiology, as well as a number of pathological states, including cancer. The IGF axis has been shown to play roles in the promotion of cell proliferation and the inhibition of cell death.

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Species
Canine (2)
Cynomolgus (3)
Human (29)
Mouse (10)
Rat (1)
Rhesus (3)
Expression System
Baculovirus Insect Cells (2)
E. coli (5)
HEK293 Cells (38)
P. pastoris (Yeast) (3)
Tag
C-6xHis (5)
C-6xHis-Avi (1)
C-His (15)
C-His-Avi (1)
C-hFc (7)
C-hFc-Avi (1)
GST (1)
His (1)
N-His (5)
N-His-Avi (1)
N-T7 (1)
N-hFc (3)
Tag Free (8)
Cat No. product name / Synonyms Species Expression System
TMPY-02295 IGFBP-7 Protein, Human, Recombinant (aa 1-282, hFc)
IGFBP-7 Protein, Human, Recombinant (aa 1-282, hFc)
Human HEK293 Cells
IGFBP-7 Protein, Human, Recombinant (aa 1-282, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 53.5 kDa and the acces...
TMPY-06982 IGF1/IGF-I Protein, Human, Recombinant
IGF1/IGF-I Protein, Human, Recombinant
Human E. coli
IGF1/IGF-I Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 7.8 KDa. and the accession number is P05019-1...
TMPY-06982 IGF1/IGF-I Protein, Human, Recombinant
IGF1/IGF-I Protein, Human, Recombinant
Human E. coli
IGF1/IGF-I Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 7.8 KDa. and the accession number is P05019-1...
TMPY-06982 IGF1/IGF-I Protein, Human, Recombinant
IGF1/IGF-I Protein, Human, Recombinant
Human E. coli
IGF1/IGF-I Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 7.8 KDa. and the accession number is P05019-1...
TMPY-06982 IGF1/IGF-I Protein, Human, Recombinant
IGF1/IGF-I Protein, Human, Recombinant
Human E. coli
IGF1/IGF-I Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 7.8 KDa. and the accession number is P05019-1...
TMPY-02533 IGFBP-7 Protein, Human, Recombinant (aa 30-282, His)
IGFBP-7 Protein, Human, Recombinant (aa 30-282, His)
Human HEK293 Cells
IGFBP-7 Protein, Human, Recombinant (aa 30-282, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.6 kDa and the acce...
TMPY-00836 IGFBP-4 Protein, Human, Recombinant (His)
IGFBP-4 Protein, Human, Recombinant (His)
Human HEK293 Cells
IGFBP-4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.4 kDa and the accession numbe...
TMPY-04508 IGFBP-7 Protein, Mouse, Recombinant (aa 1-281, hFc)
IGFBP-7 Protein, Mouse, Recombinant (aa 1-281, hFc)
Mouse HEK293 Cells
IGFBP-7 Protein, Mouse, Recombinant (aa 1-281, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 53.3 kDa and the acces...
IGFBP-7 Protein, Human, Recombinant (aa 1-282, hFc)
TMPY-02295
IGFBP-7 Protein, Human, Recombinant (aa 1-282, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 53.5 kDa and the acces...
IGF1/IGF-I Protein, Human, Recombinant
TMPY-06982
IGF1/IGF-I Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 7.8 KDa. and the accession number is P05019-1...
IGF1/IGF-I Protein, Human, Recombinant
TMPY-06982
IGF1/IGF-I Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 7.8 KDa. and the accession number is P05019-1...
IGF1/IGF-I Protein, Human, Recombinant
TMPY-06982
IGF1/IGF-I Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 7.8 KDa. and the accession number is P05019-1...
IGF1/IGF-I Protein, Human, Recombinant
TMPY-06982
IGF1/IGF-I Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 7.8 KDa. and the accession number is P05019-1...
IGFBP-7 Protein, Human, Recombinant (aa 30-282, His)
TMPY-02533
IGFBP-7 Protein, Human, Recombinant (aa 30-282, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.6 kDa and the acce...
IGFBP-4 Protein, Human, Recombinant (His)
TMPY-00836
IGFBP-4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.4 kDa and the accession numbe...
IGFBP-7 Protein, Mouse, Recombinant (aa 1-281, hFc)
TMPY-04508
IGFBP-7 Protein, Mouse, Recombinant (aa 1-281, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 53.3 kDa and the acces...
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TargetMol