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Insulin-like Growth Factors, IGFs

The insulin-like growth factors (IGFs) are proteins with high sequence similarity to insulin. IGFs are part of a complex system that cells use to communicate with their physiologic environment. This complex system (often referred to as the IGF "axis") consists of two cell-surface receptors (IGF1R and IGF2R), two ligands (IGF-1 and IGF-2), a family of seven high-affinity IGF-binding proteins (IGFBP1 to IGFBP7), as well as associated IGFBP degrading enzymes, referred to collectively as proteases. The IGF "axis" is also commonly referred to as the Growth Hormone/IGF-1 Axis. Insulin-like growth factor 1 (IGF-1) is mainly secreted by the liver as a result of stimulation by growth hormone (GH). IGF-1 is important for both the regulation of normal physiology, as well as a number of pathological states, including cancer. The IGF axis has been shown to play roles in the promotion of cell proliferation and the inhibition of cell death.

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Species
Canine (2)
Cynomolgus (3)
Human (29)
Mouse (10)
Rat (1)
Rhesus (3)
Expression System
Baculovirus Insect Cells (2)
E. coli (5)
HEK293 Cells (38)
P. pastoris (Yeast) (3)
Tag
C-6xHis (5)
C-6xHis-Avi (1)
C-His (15)
C-His-Avi (1)
C-hFc (7)
C-hFc-Avi (1)
GST (1)
His (1)
N-His (5)
N-His-Avi (1)
N-T7 (1)
N-hFc (3)
Tag Free (8)
Cat No. product name / Synonyms Species Expression System
TMPY-00837 IGFBP-4 Protein, Mouse, Recombinant (His)
IGFBP-4 Protein, Mouse, Recombinant (His)
Mouse HEK293 Cells
IGFBP-4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.2 kDa and the accession numbe...
TMPY-01762 IGF2BP-2 Protein, Human, Recombinant (His & GST)
IGF2BP-2 Protein, Human, Recombinant (His & GST)
Human Baculovirus Insect Cells
Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) is a member of the IGF-II mRNA-binding protein (IMP) family. IGF2BP2 is a member of a family of mRN...
TMPY-02119 IGFBP-6 Protein, Human, Recombinant (His)
IGFBP-6 Protein, Human, Recombinant (His)
Human HEK293 Cells
IGFBP-6 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 23.9 kDa and the accession numbe...
TMPY-02296 IGFBP-7 Protein, Human, Recombinant (aa 1-282, His)
IGFBP-7 Protein, Human, Recombinant (aa 1-282, His)
Human HEK293 Cells
IGFBP-7 Protein, Human, Recombinant (aa 1-282, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.9 kDa and the acces...
TMPY-02920 IGFBP-1 Protein, Rhesus, Recombinant (His)
IGFBP-1 Protein, Rhesus, Recombinant (His)
Rhesus HEK293 Cells
IGFBP-1 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.7 kDa and the accession numb...
TMPY-02969 IGFBP-2 Protein, Rhesus, Recombinant (His)
IGFBP-2 Protein, Rhesus, Recombinant (His)
Rhesus HEK293 Cells
IGFBP-2 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.8 kDa and the accession numb...
TMPY-03249 IGFBP-4 Protein, Cynomolgus, Recombinant (His)
IGFBP-4 Protein, Cynomolgus, Recombinant (His)
Cynomolgus HEK293 Cells
IGFBP-4 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.4 kDa.
TMPY-03251 IGFBP-3 Protein, Cynomolgus, Recombinant (His)
IGFBP-3 Protein, Cynomolgus, Recombinant (His)
Cynomolgus HEK293 Cells
IGFBP-3 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.1 kDa.
TMPY-04213 IGFBP-2 Protein, Mouse, Recombinant (His)
IGFBP-2 Protein, Mouse, Recombinant (His)
Mouse HEK293 Cells
IGFBP-2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31 kDa and the accession number ...
TMPY-04319 IGFBP-2 Protein, Mouse, Recombinant (hFc)
IGFBP-2 Protein, Mouse, Recombinant (hFc)
Mouse HEK293 Cells
IGFBP-2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 56.6 kDa and the accession numbe...
TMPY-04513 IGFBP-6 Protein, Rat, Recombinant (His)
IGFBP-6 Protein, Rat, Recombinant (His)
Rat HEK293 Cells
IGFBP-6 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.9 kDa and the accession number ...
TMPY-04878 IGF1/IGF-I Protein, Mouse, Recombinant
IGF1/IGF-I Protein, Mouse, Recombinant
Mouse P. pastoris (Yeast)
IGF1/IGF-I Protein, Mouse, Recombinant is expressed in yeast. The predicted molecular weight is 7.7 kDa and the accession number is E9PU89.
TMPY-04942 IGF1 LR3 Protein, Human, Recombinant
IGF1 LR3 Protein, Human, Recombinant
Human P. pastoris (Yeast)
IGF1 LR3 Protein, Human, Recombinant is expressed in yeast. The predicted molecular weight is 9.1 kDa and the accession number is P05019-1.
TMPY-06644 IGFBP-7 Protein, Human, Recombinant (hFc & Avi), Biotinylated
IGFBP-7 Protein, Human, Recombinant (hFc & Avi), Biotinylated
Human HEK293 Cells
IGFBP-7 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 54.9...
TMPY-06649 IGFBP-7 Protein, Human, Recombinant (His & Avi), Biotinylated
IGFBP-7 Protein, Human, Recombinant (His & Avi), Biotinylated
Human HEK293 Cells
IGFBP-7 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 29.3...
TMPY-06848 IGFBP-7 Protein, Human, Recombinant (K95R, His)
IGFBP-7 Protein, Human, Recombinant (K95R, His)
Human HEK293 Cells
IGFBP-7 Protein, Human, Recombinant (K95R, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.59 kDa and the accessio...
TMPY-06879 IGFBP-7 Protein, Mouse, Recombinant (aa 26-281, His)
IGFBP-7 Protein, Mouse, Recombinant (aa 26-281, His)
Mouse HEK293 Cells
IGFBP-7 Protein, Mouse, Recombinant (aa 26-281, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.69 kDa and the acc...
TMPY-05206 IGFBP-5 Protein, Human, Recombinant (His)
IGFBP-5 Protein, Human, Recombinant (His)
Human Baculovirus Insect Cells
IGFBP-5 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 30 kDa and the accession numbe...
TMPY-00835 IGFBP-3 Protein, Human, Recombinant (His)
IGFBP-3 Protein, Human, Recombinant (His)
Human HEK293 Cells
IGFBP-3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31 kDa and the accession number ...
TMPY-02118 IGFBP-6 Protein, Mouse, Recombinant (His)
IGFBP-6 Protein, Mouse, Recombinant (His)
Mouse HEK293 Cells
IGFBP-6 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number ...
IGFBP-4 Protein, Mouse, Recombinant (His)
TMPY-00837
IGFBP-4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.2 kDa and the accession numbe...
IGF2BP-2 Protein, Human, Recombinant (His & GST)
TMPY-01762
Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) is a member of the IGF-II mRNA-binding protein (IMP) family. IGF2BP2 is a member of a family of mRN...
IGFBP-6 Protein, Human, Recombinant (His)
TMPY-02119
IGFBP-6 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 23.9 kDa and the accession numbe...
IGFBP-7 Protein, Human, Recombinant (aa 1-282, His)
TMPY-02296
IGFBP-7 Protein, Human, Recombinant (aa 1-282, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.9 kDa and the acces...
IGFBP-1 Protein, Rhesus, Recombinant (His)
TMPY-02920
IGFBP-1 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.7 kDa and the accession numb...
IGFBP-2 Protein, Rhesus, Recombinant (His)
TMPY-02969
IGFBP-2 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.8 kDa and the accession numb...
IGFBP-4 Protein, Cynomolgus, Recombinant (His)
TMPY-03249
IGFBP-4 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.4 kDa.
IGFBP-3 Protein, Cynomolgus, Recombinant (His)
TMPY-03251
IGFBP-3 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.1 kDa.
IGFBP-2 Protein, Mouse, Recombinant (His)
TMPY-04213
IGFBP-2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31 kDa and the accession number ...
IGFBP-2 Protein, Mouse, Recombinant (hFc)
TMPY-04319
IGFBP-2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 56.6 kDa and the accession numbe...
IGFBP-6 Protein, Rat, Recombinant (His)
TMPY-04513
IGFBP-6 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.9 kDa and the accession number ...
IGF1/IGF-I Protein, Mouse, Recombinant
TMPY-04878
IGF1/IGF-I Protein, Mouse, Recombinant is expressed in yeast. The predicted molecular weight is 7.7 kDa and the accession number is E9PU89.
IGF1 LR3 Protein, Human, Recombinant
TMPY-04942
IGF1 LR3 Protein, Human, Recombinant is expressed in yeast. The predicted molecular weight is 9.1 kDa and the accession number is P05019-1.
IGFBP-7 Protein, Human, Recombinant (hFc & Avi), Biotinylated
TMPY-06644
IGFBP-7 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 54.9...
IGFBP-7 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-06649
IGFBP-7 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 29.3...
IGFBP-7 Protein, Human, Recombinant (K95R, His)
TMPY-06848
IGFBP-7 Protein, Human, Recombinant (K95R, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.59 kDa and the accessio...
IGFBP-7 Protein, Mouse, Recombinant (aa 26-281, His)
TMPY-06879
IGFBP-7 Protein, Mouse, Recombinant (aa 26-281, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.69 kDa and the acc...
IGFBP-5 Protein, Human, Recombinant (His)
TMPY-05206
IGFBP-5 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 30 kDa and the accession numbe...
IGFBP-3 Protein, Human, Recombinant (His)
TMPY-00835
IGFBP-3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31 kDa and the accession number ...
IGFBP-6 Protein, Mouse, Recombinant (His)
TMPY-02118
IGFBP-6 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number ...
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