The insulin-like growth factors (IGFs) are proteins with high sequence similarity to insulin. IGFs are part of a complex system that cells use to communicate with their physiologic environment. This complex system (often referred to as the IGF "axis") consists of two cell-surface receptors (IGF1R and IGF2R), two ligands (IGF-1 and IGF-2), a family of seven high-affinity IGF-binding proteins (IGFBP1 to IGFBP7), as well as associated IGFBP degrading enzymes, referred to collectively as proteases. The IGF "axis" is also commonly referred to as the Growth Hormone/IGF-1 Axis. Insulin-like growth factor 1 (IGF-1) is mainly secreted by the liver as a result of stimulation by growth hormone (GH). IGF-1 is important for both the regulation of normal physiology, as well as a number of pathological states, including cancer. The IGF axis has been shown to play roles in the promotion of cell proliferation and the inhibition of cell death.
Cat No. | product name / Synonyms | Species | Expression System |
---|---|---|---|
TMPY-00837 | IGFBP-4 Protein, Mouse, Recombinant (His)
IGFBP-4 Protein, Mouse, Recombinant (His)
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Mouse | HEK293 Cells |
IGFBP-4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.2 kDa and the accession numbe... | |||
TMPY-01762 | IGF2BP-2 Protein, Human, Recombinant (His & GST)
IGF2BP-2 Protein, Human, Recombinant (His & GST)
|
Human | Baculovirus Insect Cells |
Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) is a member of the IGF-II mRNA-binding protein (IMP) family. IGF2BP2 is a member of a family of mRN... | |||
TMPY-02119 | IGFBP-6 Protein, Human, Recombinant (His)
IGFBP-6 Protein, Human, Recombinant (His)
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Human | HEK293 Cells |
IGFBP-6 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 23.9 kDa and the accession numbe... | |||
TMPY-02296 | IGFBP-7 Protein, Human, Recombinant (aa 1-282, His)
IGFBP-7 Protein, Human, Recombinant (aa 1-282, His)
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Human | HEK293 Cells |
IGFBP-7 Protein, Human, Recombinant (aa 1-282, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.9 kDa and the acces... | |||
TMPY-02920 | IGFBP-1 Protein, Rhesus, Recombinant (His)
IGFBP-1 Protein, Rhesus, Recombinant (His)
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Rhesus | HEK293 Cells |
IGFBP-1 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.7 kDa and the accession numb... | |||
TMPY-02969 | IGFBP-2 Protein, Rhesus, Recombinant (His)
IGFBP-2 Protein, Rhesus, Recombinant (His)
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Rhesus | HEK293 Cells |
IGFBP-2 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.8 kDa and the accession numb... | |||
TMPY-03249 | IGFBP-4 Protein, Cynomolgus, Recombinant (His)
IGFBP-4 Protein, Cynomolgus, Recombinant (His)
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Cynomolgus | HEK293 Cells |
IGFBP-4 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.4 kDa. | |||
TMPY-03251 | IGFBP-3 Protein, Cynomolgus, Recombinant (His)
IGFBP-3 Protein, Cynomolgus, Recombinant (His)
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Cynomolgus | HEK293 Cells |
IGFBP-3 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.1 kDa. | |||
TMPY-04213 | IGFBP-2 Protein, Mouse, Recombinant (His)
IGFBP-2 Protein, Mouse, Recombinant (His)
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Mouse | HEK293 Cells |
IGFBP-2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31 kDa and the accession number ... | |||
TMPY-04319 | IGFBP-2 Protein, Mouse, Recombinant (hFc)
IGFBP-2 Protein, Mouse, Recombinant (hFc)
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Mouse | HEK293 Cells |
IGFBP-2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 56.6 kDa and the accession numbe... | |||
TMPY-04513 | IGFBP-6 Protein, Rat, Recombinant (His)
IGFBP-6 Protein, Rat, Recombinant (His)
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Rat | HEK293 Cells |
IGFBP-6 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.9 kDa and the accession number ... | |||
TMPY-04878 | IGF1/IGF-I Protein, Mouse, Recombinant
IGF1/IGF-I Protein, Mouse, Recombinant
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Mouse | P. pastoris (Yeast) |
IGF1/IGF-I Protein, Mouse, Recombinant is expressed in yeast. The predicted molecular weight is 7.7 kDa and the accession number is E9PU89. | |||
TMPY-04942 | IGF1 LR3 Protein, Human, Recombinant
IGF1 LR3 Protein, Human, Recombinant
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Human | P. pastoris (Yeast) |
IGF1 LR3 Protein, Human, Recombinant is expressed in yeast. The predicted molecular weight is 9.1 kDa and the accession number is P05019-1. | |||
TMPY-06644 | IGFBP-7 Protein, Human, Recombinant (hFc & Avi), Biotinylated
IGFBP-7 Protein, Human, Recombinant (hFc & Avi), Biotinylated
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Human | HEK293 Cells |
IGFBP-7 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 54.9... | |||
TMPY-06649 | IGFBP-7 Protein, Human, Recombinant (His & Avi), Biotinylated
IGFBP-7 Protein, Human, Recombinant (His & Avi), Biotinylated
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Human | HEK293 Cells |
IGFBP-7 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 29.3... | |||
TMPY-06848 | IGFBP-7 Protein, Human, Recombinant (K95R, His)
IGFBP-7 Protein, Human, Recombinant (K95R, His)
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Human | HEK293 Cells |
IGFBP-7 Protein, Human, Recombinant (K95R, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.59 kDa and the accessio... | |||
TMPY-06879 | IGFBP-7 Protein, Mouse, Recombinant (aa 26-281, His)
IGFBP-7 Protein, Mouse, Recombinant (aa 26-281, His)
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Mouse | HEK293 Cells |
IGFBP-7 Protein, Mouse, Recombinant (aa 26-281, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.69 kDa and the acc... | |||
TMPY-05206 | IGFBP-5 Protein, Human, Recombinant (His)
IGFBP-5 Protein, Human, Recombinant (His)
|
Human | Baculovirus Insect Cells |
IGFBP-5 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 30 kDa and the accession numbe... | |||
TMPY-00835 | IGFBP-3 Protein, Human, Recombinant (His)
IGFBP-3 Protein, Human, Recombinant (His)
|
Human | HEK293 Cells |
IGFBP-3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31 kDa and the accession number ... | |||
TMPY-02118 | IGFBP-6 Protein, Mouse, Recombinant (His)
IGFBP-6 Protein, Mouse, Recombinant (His)
|
Mouse | HEK293 Cells |
IGFBP-6 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number ... |