Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Geranylacetone has trypanostatic activity and could protect animals against the T. congolense-induced anaemia through the inhibition of sialidase and/or the protection of the parasite-induced hepatosplenomegaly.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
100 mg | Inquiry | $ 50.00 | |
1 mL * 10 mM (in DMSO) | Inquiry | $ 50.00 |
Description | Geranylacetone has trypanostatic activity and could protect animals against the T. congolense-induced anaemia through the inhibition of sialidase and/or the protection of the parasite-induced hepatosplenomegaly. |
In vivo | Geranylacetone was used to treat T. congolense infected rats, at a dose of 50 and 100 mg/kg BW, for 14 days where it was found to reduce the parasite burden in the infected animals.?Moreover, 100 mg/kg BW of geranylacetone significantly (p 0.05) ameliorated the anaemia, hepatic and renal damages caused by the parasite.?This is in addition to the alleviation of the parasite-induced hepatosplenomegaly and upsurge in free serum sialic acid levels in the infected animals which were associated with the observed anaemia amelioration by the compound[1]. |
Source |
Molecular Weight | 194.31 |
Formula | C13H22O |
CAS No. | 3796-70-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Geranylacetone 3796-70-1 Others inhibitor inhibit