keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
[Leu5]-Enkephalin, amide acetate is a δ opioid receptor agonist.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
2 mg | In stock | $ 32.00 | |
5 mg | In stock | $ 47.00 | |
10 mg | In stock | $ 67.00 | |
25 mg | In stock | $ 126.00 | |
50 mg | In stock | $ 189.00 | |
100 mg | In stock | $ 285.00 | |
200 mg | In stock | $ 427.00 |
Description | [Leu5]-Enkephalin, amide acetate is a δ opioid receptor agonist. |
In vitro | [Leu5]-Enkephalin causes concentration-dependent, reversible inhibition of pelvic nerve-evoked contractions, with an IC50 of 2.1 nM.[1] |
In vivo | Levels of [Leu5]-Enkephalin are significantly increased in the nucleus raphe magnus (NRM) of rats 2 weeks after the injection of complete Freund's adjuvant (CFA) (1.02±0.2 pmol/mg protein) as compared with saline-treated rats (0.49±0.04 pmol/mg protein; p<0.01). Tissue levels of [Leu5]-Enkephalin are uniformly increased in the caudal ventrolateral periaqueductal gray (PAG) 4 hr (1.15±0.25 pmol/mg protein), 4 d (1.16±0.18 pmol/mg protein), and 2 weeks (1.18±0.17 pmol/mg protein) after the injection of CFA as compared with saline-treated rats (0.55±0.03 pmol/mg protein; p<0.05, all times). A smaller increase in the levels of [Leu5]-Enkephalin occurred in the rostral aspect of the ventrolateral PAG at all time points. Finally, levels of [Leu5]-Enkephalin are also increased in the contralateral microcellular tegmental nucleus 4 d after the injection of CFA (0.53±0.04 pmol/mg protein) compared with levels in saline-treated rats (0.38±0.02 pmol/mg protein; p<0.05)[2]. |
Synonyms | [Leu5]-Enkephalin, amide acetate(60117-24-0 free base) |
Molecular Weight | 614.69 |
Formula | C30H42N6O8 |
CAS No. | TP1113L |
keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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[Leu5]-Enkephalin, amide acetate TP1113L Endocrinology/Hormones GPCR/G Protein Neuroscience Opioid Receptor [Leu5]Enkephalin, amide acetate [Leu5]-Enkephalin, amide acetate(60117-24-0 free base) [Leu5]-Enkephalin, amide Acetate [Leu-5]-Enkephalin, amide acetate [Leu5] Enkephalin, amide acetate inhibitor inhibit