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Zandatrigine

Catalog No. T39630 CAS 2154406-04-7

Synonyms: XEN901, NBI-921352

NBI-921352 is a blocker of Sodium Channel protein type 8 subunit alpha and can be used in studies about nervous system pathologies of epilepsy treatment.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Zandatrigine, CAS 2154406-04-7

Pack Size	Availability	Price/USD
1 mg	In stock	$ 119.00
2 mg	In stock	$ 176.00
5 mg	In stock	$ 297.00
10 mg	In stock	$ 488.00
25 mg	In stock	$ 785.00
50 mg	In stock	$ 1,120.00
100 mg	In stock	$ 1,480.00
1 mL * 10 mM (in DMSO)	In stock	$ 327.00

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Purity: 99.81%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

NBI-921352 is a blocker of sodium channel protein type 8 subunit alpha and can be used in studies about nervous system pathologies of epilepsy treatment.

Synonyms	XEN901, NBI-921352
Molecular Weight	460.59
Formula	C22H25FN4O2S2
CAS No.	2154406-04-7

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 2 years

Solubility Information

DMSO: 112.5mg/mL (244.3mM), Need ultrasonic

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Jean-Christophe ANDREZ, et al. Benzenesulfonamide compounds and their use as therapeutic agents. Patent WO2017201468A1.

Related compound libraries

This product is contained In the following compound libraries：

Bioactive Compound Library Inhibitor Library Anti-Cancer Clinical Compound Library Anti-Cancer Drug Library Drug Repurposing Compound Library Anti-Cancer Compound Library Clinical Compound Library Bioactive Compounds Library Max

Related Products

Related compounds with same targets

Bulleyaconitine A Halazone Ecdysone Benzocaine hydrochloride Sparteine sulfate 4-Hydroxycinnamamide Veratridine GX-674

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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
Enter 197.13 into the Molecular Weight (MW) box
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The answer of 19.713 mg appears in the Mass box

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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
Enter 10 into the Concentration (start) box and select the correct unit (millimolar)
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Zandatrigine 2154406-04-7 Membrane transporter/Ion channel Sodium Channel XEN901 NBI-921352 inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.