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Zandatrigine

Name: Zandatrigine
Brand: TargetMol
SKU: T39630
Price: 119 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T39630Cas No. 2154406-04-7

Alias XEN901, NBI-921352

Zandatrigine (NBI-921352) is a sodium channel protein type 8 subunit alpha blocker, suitable for studies on epilepsy treatment and nervous system pathologies.

Zandatrigine

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Purity: 99.98%

Catalog No. T39630Alias XEN901, NBI-921352Cas No. 2154406-04-7

Zandatrigine (NBI-921352) is a sodium channel protein type 8 subunit alpha blocker, suitable for studies on epilepsy treatment and nervous system pathologies.

Pack Size	Price	Availability
1 mg	$119	In Stock
2 mg	$176	In Stock
5 mg	$297	In Stock
10 mg	$488	In Stock
25 mg	$785	In Stock
50 mg	$1,120	In Stock
100 mg	$1,480	In Stock
1 mL x 10 mM (in DMSO)	$327	In Stock

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Batch Information

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Purity:99.98%

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COA LCMS HNMR

Product Introduction

Bioactivity

Description	Zandatrigine (NBI-921352) is a sodium channel protein type 8 subunit alpha blocker, suitable for studies on epilepsy treatment and nervous system pathologies.
Synonyms	XEN901, NBI-921352

Chemical Properties

Molecular Weight	460.59
Formula	C₂₂H₂₅FN₄O₂S₂
Cas No.	2154406-04-7
Smiles	CN([C@H]1CCN(Cc2ccccc2)C1)c1cc(F)c(cc1C)S(=O)(=O)Nc1cscn1

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 112.5 mg/mL (244.3 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.1711 mL	10.8556 mL	21.7113 mL	108.5564 mL
5 mM	0.4342 mL	2.1711 mL	4.3423 mL	21.7113 mL
10 mM	0.2171 mL	1.0856 mL	2.1711 mL	10.8556 mL
20 mM	0.1086 mL	0.5428 mL	1.0856 mL	5.4278 mL
50 mM	0.0434 mL	0.2171 mL	0.4342 mL	2.1711 mL
100 mM	0.0217 mL	0.1086 mL	0.2171 mL	1.0856 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc