Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Thalidomide-NH-CH2-COOH ((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)glycine) is a synthesized E3 ligase ligand-linker conjugate containing a Thalidomide-based cereblon ligand and a linker.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 37.00 | |
10 mg | In stock | $ 51.00 | |
25 mg | In stock | $ 80.00 | |
50 mg | In stock | $ 115.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 50.00 |
Description | Thalidomide-NH-CH2-COOH ((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)glycine) is a synthesized E3 ligase ligand-linker conjugate containing a Thalidomide-based cereblon ligand and a linker. |
In vitro | PROTACs contain two different ligands connected by a linker; one of them is a ligand for an E3 ubiquitin ligase and the other one is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Synonyms | 2-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]acetic acid, (2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)glycine |
Molecular Weight | 331.28 |
Formula | C15H13N3O6 |
CAS No. | 927670-97-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 42.5 mg/mL (128.29 mM)
You can also refer to dose conversion for different animals. More
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Thalidomide-NH-CH2-COOH 927670-97-1 PROTAC Ligand for E3 Ligase inhibit Ligands for E3 Ligase E3 ligase-recruiting Moiety Inhibitor Thalidomide NH CH2 COOH ThalidomideNHCH2COOH cereblon Thalidomide-NH-CH-2-COOH CRBN 2-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]acetic acid Thalidomide (2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)glycine inhibitor