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Terminolic acid

Catalog No. TN6722   CAS 564-13-6
Synonyms: 2α,6β,23-trihydroxyl oleanolic acid

Terminolic acid (2α,6β,23-trihydroxyl oleanolic acid) is a pentacyclic triterpenoid glucoside isolated from Combretum racemosum, can inhibit the pro-inflammatory cytokines by binding to receptor active site of IL-1β and IL-6, and enhance anti-inflammatory cytokines by binding to IL-4 receptor binding sites. It also exhibits moderate antibacterial activity.

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Terminolic acid Chemical Structure
Terminolic acid, CAS 564-13-6
Pack Size Availability Price/USD Quantity
1 mg In stock $ 50.00
5 mg In stock $ 112.00
10 mg In stock $ 163.00
25 mg In stock $ 272.00
50 mg In stock $ 393.00
100 mg In stock $ 588.00
1 mL * 10 mM (in DMSO) In stock $ 170.00
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Purity: 99.79%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Terminolic acid (2α,6β,23-trihydroxyl oleanolic acid) is a pentacyclic triterpenoid glucoside isolated from Combretum racemosum, can inhibit the pro-inflammatory cytokines by binding to receptor active site of IL-1β and IL-6, and enhance anti-inflammatory cytokines by binding to IL-4 receptor binding sites. It also exhibits moderate antibacterial activity.
Synonyms 2α,6β,23-trihydroxyl oleanolic acid
Molecular Weight 504.7
Formula C30H48O6
CAS No. 564-13-6

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 45 mg/mL (89.16 mM)

TargetMolReferences and Literature

1. Legiawati L, et, al. In silico study of Centella asiatica active compounds as anti-inflammatory agent by decreasing Il-1 and Il-6 activity, promoting Il-4 activity. /J. Pharm. Sci. & Res. Vol. 10(9), 2018, 2142-2147. 2. Gossan DPA, et, al. Antibacterial and cytotoxic triterpenoids from the roots of Combretum racemosum. Fitoterapia. 2016 Apr;110:89-95.

Related compound libraries

This product is contained In the following compound libraries:
Selected Plant-Sourced Compound Library Anti-Aging Compound Library Anti-infective Natural Product Library Natural Product Library NO PAINS Compound Library Anti-Infection Compound Library Anti-Bacterial Compound Library Bioactive Compounds Library Max Natural Product Library for HTS Antibiotics Library

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Keywords

Terminolic acid 564-13-6 Microbiology/Virology Antibacterial racemosum glucoside Inhibitor IL-1β antibacterial Bacterial IL-6 triterpenoid 2a,6b,23-trihydroxyl oleanolic acid IL-4 inhibit 2α,6β,23-trihydroxyl oleanolic acid cytokines inflammatory pentacyclic Combretum 2alpha,6beta,23-trihydroxyl oleanolic acid inhibitor

 

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