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Telocinobufagin

Catalog No. T4A2462 CAS 472-26-4

Synonyms: Telobufotoxin, Telocinobufogenin

1. Telocinobufagin (Telobufotoxin) is the major endogenous digitalis-like factor. 2. Telocinobufagin significantly decreases the bacterial burdens in the spleen and prolongs the survival time of FIST-immunized mice challenged with live S. typhimurium. 3. Telocinobufagin has immunomodulatory activity, can enhance a Th1 immune response to control intracellular infections, could be developed as a novel immunotherapeutic agent to treat cancer and other immune-mediated diseases.

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Telocinobufagin, CAS 472-26-4

Pack Size	Availability	Price/USD
1 mg	In stock	$ 57.00
5 mg	In stock	$ 139.00
10 mg	In stock	$ 222.00
25 mg	In stock	Inquiry
50 mg	In stock	Inquiry
1 mL * 10 mM (in DMSO)	In stock	$ 155.00

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Purity: 99.74%

Purity: 98.42%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	Telobufotoxin, Telocinobufogenin
Molecular Weight	402.52
Formula	C24H34O5
CAS No.	472-26-4

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 60 mg/mL (149.06 mM)

References and Literature

1. Wu S C , Fu B D , Shen H Q , et al. Telocinobufagin enhances the Th1 immune response and protects against Salmonella typhimurium infection[J]. International Immunopharmacology, 2015, 25(2):353-362.

Citations

1. Ma X, Xu W, Jin X, et al.Telocinobufagin inhibits osteosarcoma growth and metastasis by inhibiting the JAK2/STAT3 signaling pathway.European Journal of Pharmacology.2023: 175529.

Related compound libraries

This product is contained In the following compound libraries：

Traditional Chinese Medicine Monomer Library Natural Product Library for HTS RO5 Drug-like Natural Product Library Immunology/Inflammation Compound Library Bioactive Compound Library Anti-Cancer Compound Library Anti-Tumor Natural Product Library Natural Product Library Anti-infective Natural Product Library Human Metabolite Library

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Telocinobufagin 472-26-4 Others Telobufotoxin Inhibitor inhibit Telocinobufogenin inhibitor

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