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S29434

Catalog No. T7149 CAS 874484-20-5

S29434 (NMDPEF) is a potent, competitiveinhibitor of quinone reductase 2 (QR2;IC50:5-16nM).

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S29434, CAS 874484-20-5

Pack Size	Availability	Price/USD
1 mg	In stock	$ 51.00
5 mg	In stock	$ 122.00
10 mg	In stock	$ 197.00
25 mg	In stock	$ 396.00
50 mg	Inquiry	$ 589.00
1 mL * 10 mM (in DMSO)	In stock	$ 133.00

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Purity: 99.92%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	S29434 (NMDPEF) is a potent, competitiveinhibitor of quinone reductase 2 (QR2;IC50:5-16nM).
Targets&IC50	QR2 (human):5-16 nM

Molecular Weight	374.39
Formula	C21H18N4O3
CAS No.	874484-20-5

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 12.5 mg/mL (33.39 mM)

References and Literature

1. Boutin JA, Bouillaud F, Janda E,et al.S29434, a Quinone Reductase 2 Inhibitor: Main Biochemical and Cellular Characterization[J].Mol Pharmacol. 2019 Mar;95(3):269-285. 2. Laure-Estelle C , Nambinina R , Serena S , et al. Role of Quinone Reductase 2 in the Antimalarial Properties of Indolone-Type Derivatives[J]. Molecules, 2017, 22(2):210-.

Related compound libraries

This product is contained In the following compound libraries：

Inhibitor Library Metabolism Compound Library Bioactive Compound Library Mitochondria-Targeted Compound Library Anti-Fibrosis Compound Library NO PAINS Compound Library Anti-Metabolism Disease Compound Library Anti-COVID-19 Compound Library Bioactive Compounds Library Max Anti-Aging Compound Library

Related Products

Related compounds with same targets

Diphenyleneiodonium chloride KL1333 AKR1C3-IN-1 APX-115 free base Carvedilol phosphate hemihydrate Acetohexamide GKT136901 Resveratrol

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

S29434 874484-20-5 Autophagy Metabolism NADPH cell-permeable inhibit selective S-29434 HepG2 mice NMDPEF ROS S 29434 Inhibitor memory inhibitor

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.