Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Pinokalant (LOE-908) is a novel non-selective cation channel inhibitor.Pinokalant significantly reduces cortical infarct volume in in vivo experiments, improves the metabolic and electrophysiological status of the ischemic penumbra region, and reduces the size of the lesion on magnetic resonance images in the acute phase after middle cerebral artery occlusion in rats.Pinokalant is a potential SARS-CoV-2 protease inhibitor for the study of stroke.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 195.00 | |
5 mg | In stock | $ 430.00 | |
10 mg | In stock | $ 636.00 | |
25 mg | In stock | $ 987.00 | |
50 mg | In stock | $ 1,360.00 |
Description | Pinokalant (LOE-908) is a novel non-selective cation channel inhibitor.Pinokalant significantly reduces cortical infarct volume in in vivo experiments, improves the metabolic and electrophysiological status of the ischemic penumbra region, and reduces the size of the lesion on magnetic resonance images in the acute phase after middle cerebral artery occlusion in rats.Pinokalant is a potential SARS-CoV-2 protease inhibitor for the study of stroke. |
In vitro | Pinokalant leads to a substantial decrease in cortical infarct volume, reducing it from 33.8 mm³ to 24.5 mm³.[1] |
Synonyms | LOE-908 |
Molecular Weight | 712.83 |
Formula | C41H48N2O9 |
CAS No. | 149759-26-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Pinokalant 149759-26-2 Membrane transporter/Ion channel Microbiology/Virology SARS-CoV TRP/TRPV Channel LOE-908 LOE 908 LOE908 inhibitor inhibit