Powder: -20°C for 3 years | In solvent: -80°C for 2 years
PF-562271 is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM in cell-free assays, ~10-fold less potent for PYK2 than FAK and >100-fold selectivity against other protein kinases, except for some CDKs.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 71.00 | |
10 mg | In stock | $ 98.00 | |
25 mg | In stock | $ 155.00 | |
50 mg | In stock | $ 224.00 | |
100 mg | In stock | $ 331.00 |
Description | PF-562271 is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM in cell-free assays, ~10-fold less potent for Pyk2 than FAK and >100-fold selectivity against other protein kinases, except for some CDKs. |
Targets&IC50 | FAK:1.5 nM |
Synonyms | PF-562271 HCl |
Molecular Weight | 543.95 |
Formula | C21H20F3N7O3S HCl |
CAS No. | 939791-41-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 2 years
DMSO: 91 mg/mL(167.3 mM)
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
PF-562271 hydrochloride 939791-41-0 Angiogenesis Cell Cycle/Checkpoint Cytoskeletal Signaling Tyrosine Kinase/Adaptors FAK PYK2 CDK Proline-rich tyrosine kinase 2 Ewing inhibit Antitumor PF-562271 HCl PF-562271 Focal adhesion kinase Sarcoma VS-6062(hydrochloride) PTK2 protein tyrosine kinase 2 Pyk2 PF562271 hydrochloride PTK2 PF 562271 PF562271 Cancer PF 562271 hydrochloride Inhibitor Breast inhibitor