Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Narasin (sodium salt) (HainanMycin) induces tumor necrosis factor-related apoptosis-induced ligand (TRAIL)-mediated apoptosis by ER stress in glioma cells and inhibits NF-κB signaling by suppressing the phosphorylation of IκBα.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | 35 days | $ 297.00 | |
25 mg | 35 days | $ 1,390.00 |
Description | Narasin (sodium salt) (HainanMycin) induces tumor necrosis factor-related apoptosis-induced ligand (TRAIL)-mediated apoptosis by ER stress in glioma cells and inhibits NF-κB signaling by suppressing the phosphorylation of IκBα. |
In vitro | Narasin caused suicidal erythrocyte death or eryptosis. In human erythrocytes, Narasin increased annexin-V-binding indicating cell membrane scrambling with phosphatidylserine translocation to the erythrocyte surface and the decrease of forward scatter reflecting cell shrinkage, which indicated the death of erythrocyte [1]. |
In vivo | Administration of 4-48 p.p.m of narasin in the pelleted feed of New Zealand White rabbits. After 4 weeks, narasin protected rabbits from severe coccidiosis induced by E. flavescens, E. perforans E. Magna, E. Intestinalis, and E. Stiedai. In addition, narasin reduced oocyst output effectively[2]. |
Synonyms | Naracin sodium salt, naransin sodium, HainanMycin |
Molecular Weight | 787.01 |
Formula | C43H71NaO11 |
CAS No. | 58331-17-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: Soluble
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