Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Nanterinone (UK 61260), an orally available partial phosphodiesterase inhibitor, is a novel positive inotropic and balanced vasodilator compound.Nanterinone, when administered orally, results in significant improvements in acute haemodynamics, which may depend on pre-existing left ventricular filling pressures.Nanterinone is a novel positive inotropic and balanced vasodilator that has demonstrated acute hemodynamic effects in patients with mild to moderate heart failure.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 143.00 | |
5 mg | In stock | $ 360.00 | |
10 mg | In stock | $ 530.00 | |
25 mg | In stock | $ 859.00 | |
50 mg | In stock | $ 1,180.00 | |
100 mg | In stock | $ 1,590.00 | |
500 mg | In stock | $ 3,190.00 |
Description | Nanterinone (UK 61260), an orally available partial phosphodiesterase inhibitor, is a novel positive inotropic and balanced vasodilator compound.Nanterinone, when administered orally, results in significant improvements in acute haemodynamics, which may depend on pre-existing left ventricular filling pressures.Nanterinone is a novel positive inotropic and balanced vasodilator that has demonstrated acute hemodynamic effects in patients with mild to moderate heart failure. |
In vivo | Nanterinone (2 mg ; oral ; patients NYHA class II-III ; ACE) has a significant acute hemodynamic improvement and is well tolerated. Although changes in left ventricular filling pressure are more pronounced in patients with elevated pre-existing PCWP, cardiac pump function improves equally in patients with normal or low left ventricular filling pressure at baseline.[1] |
Synonyms | UK-61260, UK61260, UK 61260 |
Molecular Weight | 253.3 |
Formula | C15H15N3O |
CAS No. | 102791-47-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: Slightly soluble
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Nanterinone 102791-47-9 Metabolism PDE UK-61260 UK61260 UK 61260 inhibitor inhibit