Powder: -20°C for 3 years | In solvent: -80°C for 1 year
MTEP hydrochloride (MTEP) is non-competitive mGlu5 antagonist (IC50 and Ki of 5 nM and 16 nM, respectively)
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
2 mg | In stock | $ 35.00 | |
5 mg | In stock | $ 57.00 | |
10 mg | In stock | $ 90.00 | |
25 mg | In stock | $ 198.00 | |
50 mg | In stock | $ 395.00 | |
100 mg | In stock | $ 593.00 | |
200 mg | In stock | $ 822.00 |
Description | MTEP hydrochloride (MTEP) is non-competitive mGlu5 antagonist (IC50 and Ki of 5 nM and 16 nM, respectively) |
Targets&IC50 | mGlu5:16 nM(ki), mGlu5:5 nM |
In vivo | Male Albino Swiss mice were used, and antidepressant-like activity was evaluated using the FST.?The antidepressant-like effect of MTEP (0.3 mg/kg) was significantly antagonized by pre-treatment with the NMDA receptor agonist N-methyl-D-aspartic acid (NMDA, 75 mg/kg)[1]. |
Synonyms | 3-((2-Methyl-1,3-thiazol-4-yl)ethyn-yl)pyridine hydrochloride, MTEP |
Molecular Weight | 236.72 |
Formula | C11H9ClN2S |
CAS No. | 1186195-60-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 20 mg/mL (84.49 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
MTEP hydrochloride 1186195-60-7 Neuroscience GluR 3-((2-Methyl-1,3-thiazol-4-yl)ethyn-yl)pyridine hydrochloride Metabotropic glutamate receptors mGluR inhibit Inhibitor MTEP MTEP Hydrochloride inhibitor