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Home > GPCR/G Protein > Hedgehog/Smoothened > MK-4101

MK-4101

Catalog No. T6891    CAS 935273-79-3    Synonyms: MK4101, MK 4101,

MK-4101, an effective inhibitor of the Hedgehog pathway, has anti-tumor activity through the induction of extensive apoptosis and inhibition of proliferation in tumor cells.

Pack Size Availability Price/USD Quantity
2 mg In stock 76.00
5 mg In stock 114.00
10 mg In stock 205.00
25 mg In stock 377.00
1 mL * 10 mM (in DMSO) In stock 121.00
Bulk Size: Please Quote for Discount Please Quote for Bulk Size
Biological Activity:

Product Description:

MK-4101, an effective inhibitor of the Hedgehog pathway, has anti-tumor activity through the induction of extensive apoptosis and inhibition of proliferation in tumor cells.

Receptor:

Smoothened;

Chemical Information:
Molecular Weight 493.47
Formula C24H24F5N5O
CAS Number 935273-79-3
Solubility

Ethanol: 60 mg/mL (121.6 mM)

DMSO: 92 mg/mL (186.4 mM)

Water: <1 mg/mL

( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage store at -80°C
Remark For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ℃ for several month.
Technical Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.

Reference
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