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Lignoceric Acid

Catalog No. TN6953   CAS 557-59-5
Synonyms: tetracosanoic acid

Lignoceric Acid (tetracosanoic acid) is a 24-carbon saturated (24:0) fatty acid and a by-product of lignin production, which is synthesized in the developing brain.

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Lignoceric Acid Chemical Structure
Lignoceric Acid, CAS 557-59-5
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Lignoceric Acid (tetracosanoic acid) is a 24-carbon saturated (24:0) fatty acid and a by-product of lignin production, which is synthesized in the developing brain.
In vitro The thermogenic flux induced by Lignoceric Acid was estimated by isothermal titration calorimetry in peroxisomes isolated from HepG2 cells and from fibroblasts obtained from patients with X-ALD and healthy subjects. Heat flux induced by lignoceric acid in HepG2 peroxisomes was exothermic, indicating normal peroxisomal metabolism[2].
Synonyms tetracosanoic acid
Molecular Weight 368.64
Formula C24H48O2
CAS No. 557-59-5

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: < 1 mg/mL (insoluble or slightly soluble)

Ethanol: 1 mg/mL (2.7 mM), Sonication and heating to 50℃ are recommended.

TargetMolReferences and Literature

1. Chung HK, et al. Plasma phospholipid arachidonic acid and lignoceric acid are associated with the risk of cardioembolic stroke. Nutr Res. 2015 Nov;35(11):1001-8. 2. Anna Petroni, et al. Thermogenic flux induced by lignoceric acid in peroxisomes isolated from HepG2 cells and from X-adrenoleukodystrophy and control fibroblasts. J Cell Physiol. 2019 Aug;234(10):18344-18348.

Related compound libraries

This product is contained In the following compound libraries:
Miao medicine Compound Library Microbial Natural Product Library Human Endogenous Metabolite Library Tobacco Monomer Library Human Endogenous Metabolite Compound Library Plus Natural Product Library for HTS PBCRBS Traditional Chinese Medicine Compound Library Natural Product Library Traditional Mongolian Medicine Compound Library Food as Medicine Compound Library

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Keywords

Lignoceric Acid 557-59-5 Metabolism Endogenous Metabolite Inhibitor fatty neurodegenerative inhibit lignin tetracosanoic acid acid peroxisomal inhibitor

 

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