Powder: -20°C for 3 years | In solvent: -80°C for 1 year
UNC569, the first small-molecule MER inhibitor, inhibits Mer activation and downstream signaling through ERK1/2 and AKTwith. UNC569 shows efficacy against acute lymphoblastic leukemia in vitro and in vivo.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
2 mg | 5 days | $ 31.00 | |
5 mg | 5 days | $ 47.00 | |
10 mg | 5 days | $ 67.00 | |
25 mg | 5 days | $ 134.00 | |
1 mL * 10 mM (in DMSO) | 5 days | $ 52.00 |
Description | UNC569, the first small-molecule MER inhibitor, inhibits Mer activation and downstream signaling through ERK1/2 and AKTwith. UNC569 shows efficacy against acute lymphoblastic leukemia in vitro and in vivo. |
Targets&IC50 | OAT3:2 µM (Km), OAT1:0.85 µM (Km) |
Synonyms | Lesinurad, RDEA 594, RDEA-594, RDEA594 |
Molecular Weight | 426.26 |
Formula | C17H13BrN3NaO2S |
CAS No. | 1151516-14-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: Soluble
H2O: Insoluble
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Lesinurad sodium 1151516-14-1 Lesinurad RDEA 594 RDEA-594 RDEA594 inhibitor inhibit