Powder: -20°C for 3 years | In solvent: -80°C for 1 year
L-ascorbic acid 2-phosphate can be used as a culture medium supplement for the osteogenic differentiation of human adipose stem cells (hASCs). L-ascorbic acid 2-phosphate increases alkaline phosphatase (ALP) activity and expression of runx2A in hASCs during the osteogenic differentiation. L-ascorbic acid 2-phosphate is a long-acting vitamin C derivative that can stimulate collagen formation and expression.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 1,520.00 | |
50 mg | 6-8 weeks | $ 1,980.00 | |
100 mg | 6-8 weeks | $ 2,500.00 |
Description | L-ascorbic acid 2-phosphate can be used as a culture medium supplement for the osteogenic differentiation of human adipose stem cells (hASCs). L-ascorbic acid 2-phosphate increases alkaline phosphatase (ALP) activity and expression of runx2A in hASCs during the osteogenic differentiation. L-ascorbic acid 2-phosphate is a long-acting vitamin C derivative that can stimulate collagen formation and expression. |
Targets&IC50 | ALP: |
In vitro | A combination of Asc-2P and bFGF significantly increases cell growth, but supplementation with EGF and/or insulin does not have any additional effect .?L-Ascorbic acid 2-phosphate (50 μM-250 μM) is needed for the effective osteogenic differentiation of human adipose stem cells (hASCs), and higher concentrations of AsA2-P results in increased runx2 expression and ALP activity.?The highest proliferation, ALP activity and runx2 expression is achieved with 150 μM AsA2-P and 10 nM dexamethasone (Dex), and 250 μM AsA2-P and 5 nM Dex.L-Ascorbic acid 2-phosphate ?significantly stimulates cell growth, whereas addition of l-Ascorbic acid (Asc) ?achieves only weak growth stimulation. |
Synonyms | 2-Phospho-L-ascorbic acid |
Molecular Weight | 256.1 |
Formula | C6H9O9P |
CAS No. | 23313-12-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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L-Ascorbic acid 2-phosphate 23313-12-4 Others L-Ascorbic acid LAscorbic acid 2phosphate L Ascorbic acid 2 phosphate 2-Phospho-L-ascorbic acid inhibitor inhibit