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Hematoxylin

Catalog No. T1686 CAS 517-28-2

Synonyms: Hydroxybrazilin, Natural Black 1, Haematoxylin

Hematoxylin (Natural Black 1) is a dye obtained from the heartwood of logwood (Haematoxylon campechianum Linn., Leguminosae) used as a stain in microscopy and in the manufacture of ink.

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Hematoxylin, CAS 517-28-2

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200 mg	In stock	$ 44.00

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Purity: 97.09%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Hematoxylin (Natural Black 1) is a dye obtained from the heartwood of logwood (Haematoxylon campechianum Linn., Leguminosae) used as a stain in microscopy and in the manufacture of ink.
Targets&IC50	Aβ42 fibrillogenesis:1.6 µM (IC50)
In vivo	Hematoxylin and eosin staining is one of the most commonly used histological staining methods. Hematoxylin (Hydroxybrazilin) is a compound that forms strongly colored complexes with certain metal ions, especially with Fe(III) and Al(III) salts, and acts as a histological stain.
Source	Natural Products > Fabaceae > Haematoxylon

Synonyms	Hydroxybrazilin, Natural Black 1, Haematoxylin
Molecular Weight	302.28
Formula	C16H14O6
CAS No.	517-28-2

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 57 mg/mL (188.6 mM)

Ethanol: 57 mg/mL (188.6 mM)

H2O: 56 mg/mL (185.3 mM)

References and Literature

1. Godwin A, J Pharm Clin Sci, 2011, 1, 24-34.

Citations

1. Li H, Pang B, Nie B, et al. Dioscin promotes autophagy by regulating the AMPK-mTOR pathway in ulcerative colitis. Immunopharmacology and Immunotoxicology. 2022: 1-9. 2. Zhang M, Hao Z, Wu J, et al.Curcumin ameliorates traumatic brain injury via C1ql3-mediated microglia M2 polarization.Tissue and Cell.2023: 102164.

Related compound libraries

This product is contained In the following compound libraries：

Anti-Neurodegenerative Disease Compound Library Inhibitor Library Selected Plant-Sourced Compound Library Natural Product Library FDA-Approved & Pharmacopeia Drug Library PBCRBS Traditional Chinese Medicine Compound Library RO5 Drug-like Natural Product Library Bioactive Compound Library Bioactive Compounds Library Max Traditional Chinese Medicine Monomer Library

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Keywords

Hematoxylin 517-28-2 Neuroscience Others Beta Amyloid flavonoid Aβ42 Amyloid-β H&E nuclear β-amyloid peptide Natural Black1 Inhibitor stain Hydroxybrazilin Eosin fibrillogenesis Abeta inhibit Natural Black-1 histology Natural Black 1 Haematoxylin inhibitor

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