Powder: -20°C for 3 years | In solvent: -80°C for 1 year
FT827 is a covalent inhibitor of selective ubiquitin-specific protease 7 (USP7) (Ki=4.2 µM, Kd=7.8 µM) targeting the catalytic center of the autoinhibitory apolipoprotein form of USP7 for cancer research.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 397.00 | |
5 mg | In stock | $ 970.00 | |
25 mg | In stock | $ 1,580.00 | |
50 mg | In stock | $ 1,980.00 |
Description | FT827 is a covalent inhibitor of selective ubiquitin-specific protease 7 (USP7) (Ki=4.2 µM, Kd=7.8 µM) targeting the catalytic center of the autoinhibitory apolipoprotein form of USP7 for cancer research. |
Targets&IC50 | USP7:(kd)7.8 μM, USP7:(ki)4.2 μM |
In vitro | After incubating MCF7 cell extracts with DMSO, 1 µM or 10 µM of FT671, FT827, or 50 µM of P22077 for 60 minutes, the results demonstrated the target-specific engagement of USP7 in MCF7 cells[1]. |
Molecular Weight | 548.61 |
Formula | C27H28N6O5S |
CAS No. | 1959537-86-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 80 mg/mL (145.82 mM), Sonification is recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
FT827 1959537-86-0 Cell Cycle/Checkpoint DNA Damage/DNA Repair Ubiquitination DUB FT-827 FT 827 inhibitor inhibit