Powder: -20°C for 3 years | In solvent: -80°C for 1 year
F-1 is IC50s of 2.1 nM, 2.3 nM, 1.3 nM and 3.9 nM for ALKWT, ROS1WT, ALKL1196M and ALKG1202R, respectively. F-1 is a potent ALK and ROS1 dual inhibitor, suppresses phospho-ALK and its relative downstream signaling pathways.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 111.00 | |
5 mg | In stock | $ 239.00 | |
10 mg | In stock | $ 347.00 | |
25 mg | In stock | $ 555.00 | |
50 mg | In stock | $ 783.00 | |
100 mg | In stock | $ 1,090.00 | |
500 mg | In stock | $ 2,230.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 295.00 |
Description | F-1 is IC50s of 2.1 nM, 2.3 nM, 1.3 nM and 3.9 nM for ALKWT, ROS1WT, ALKL1196M and ALKG1202R, respectively. F-1 is a potent ALK and ROS1 dual inhibitor, suppresses phospho-ALK and its relative downstream signaling pathways. |
Targets&IC50 | ALKWT:2.1 nM, ROS1WT:2.3 nM, ALKG1202R:3.9 nM, ALKL1196M:1.3 nM |
Molecular Weight | 519.02 |
Formula | C22H27ClN8O3S |
CAS No. | 2244775-31-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 100 mg/mL (192.67 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
F-1 2244775-31-1 Angiogenesis Immunology/Inflammation Tyrosine Kinase/Adaptors ROS ROS Kinase ALK ALK tyrosine kinase receptor CD246 F 1 Anaplastic lymphoma kinase (ALK) Anaplastic lymphoma kinase Inhibitor F1 Cluster of differentiation 246 inhibit inhibitor