Shopping Cart
Remove All
Your shopping cart is currently empty
Dihydroresveratrol
Copy Product Info
😃Good
Catalog No. T3840Cas No. 58436-28-5
Alias 3,4',5-Trihydroxybibenzyl
Dihydroresveratrol (3,4',5-Trihydroxybibenzyl) is a major metabolite of resveratrol that is produced by animal-associated bacteria, including the gut microbiota. Dihydroresveratrol and dihydroresveratrol monosulfate are detectable in urine. The physiological effects of dihydroresveratrol have not been investigated.
Dihydroresveratrol
Copy Product Info😃Good
Purity: 99.88%
Catalog No. T3840Alias 3,4',5-TrihydroxybibenzylCas No. 58436-28-5
Dihydroresveratrol (3,4',5-Trihydroxybibenzyl) is a major metabolite of resveratrol that is produced by animal-associated bacteria, including the gut microbiota. Dihydroresveratrol and dihydroresveratrol monosulfate are detectable in urine. The physiological effects of dihydroresveratrol have not been investigated.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 2 mg | $30 | In Stock | In Stock | |
| 5 mg | $52 | In Stock | In Stock | |
| 10 mg | $85 | In Stock | In Stock | |
| 25 mg | $155 | In Stock | In Stock | |
| 50 mg | $248 | In Stock | In Stock | |
| 100 mg | $373 | In Stock | In Stock | |
| 200 mg | $549 | - | In Stock | |
| 1 mL x 10 mM (in DMSO) | $53 | In Stock | In Stock |
Add to Cart
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Batch Information
Select Batch
Purity:99.88%
Appearance:Solid
Color:White
Contact us for more batch information
Product Introduction
Dihydroresveratrol AI Summary
Dihydroresveratrol exhibits a multifaceted range of bioactivities across various biological systems. It demonstrates inhibitory activity against nitric oxide production in LPS-activated mouse peritoneal macrophages with an IC50 value of 76000.0 nM and shows spasmolytic activity in guinea pig ileum with an IC50 value of 1750.0 nM and an Emax of 64.1%. Additionally, Dihydroresveratrol functions as a blocker of inward and delayed rectifier potassium channels in mouse rat hybrid F11 cells, showing 39.2% and 52.0% activity, respectively, at 90 uM concentration. It also inhibits the peptidase and hydrolase activities of human recombinant LTA4H with IC50 values of 145000.0 nM and 247000.0 nM, respectively.
The compound exhibits potent cytotoxicity against human MCF7 cells with an IC50 value of 0.1 nM after 48 hours, and also shows cytotoxic effects on human K562 cells with an IC50 below 1000.0 nM. Moreover, Dihydroresveratrol has various inhibitory activities including the inhibition of human aromatase by 37.8% at 50 uM, induction of QR1 activity in mouse Hepa-1c1c7 cells with a ratio of 1.8, and inhibition of TNFalpha-activated NF-kappaB in HEK293 cells by 16.7%. The compound also demonstrates antioxidant capabilities with 14.7% DPPH free radical scavenging activity at 400 uM and shows moderate anti-proliferative activity against human MCF7 cells with an IC50 value of 30300.0 nM.
In cancer models, Dihydroresveratrol inhibits growth in various human tumor cell lines with GI50 values ranging from 22000.0 nM to 100000.0 nM. It also modulates rat GABAA alpha1beta2gamma2S receptors in Xenopus laevis oocytes, potentiating GABA-induced chloride ion current with an activity of 162.2% at 100 uM.
Tracking studies show a retention time of 30.4 minutes in C57BL/6J mouse feces and urine, and the compound influences human TRPA1 activity in HEK293 cells with varied inhibition and agonist effects on calcium influx.
Moreover, Dihydroresveratrol inhibits acid-induced transthyretin aggregation by 30.0% and shows binding affinity to transthyretin with low selectivity. The compound exhibits moderate to high activity in inhibiting tyrosinase activity in human A375 and mouse B16 cells, reducing alpha-MSH-induced melanin formation by around 78% and inducing growth inhibition of 5-6%. Lastly, it demonstrates strong antioxidant activity with a high ABTS radical scavenging activity of 4969.61 mg.equiv..
Note: Summary generated by AI. Data source: ChEMBL 
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Dihydroresveratrol (3,4',5-Trihydroxybibenzyl) is a major metabolite of resveratrol that is produced by animal-associated bacteria, including the gut microbiota. Dihydroresveratrol and dihydroresveratrol monosulfate are detectable in urine. The physiological effects of dihydroresveratrol have not been investigated. |
| Synonyms | 3,4',5-Trihydroxybibenzyl |
| Molecular Weight | 230.26 |
| Formula | C14H14O3 |
| Cas No. | 58436-28-5 |
| Smiles | Oc1ccc(CCc2cc(O)cc(O)c2)cc1 |
| Relative Density. | 1.291g/cm3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 250 mg/mL (1085.73 mM), Sonication is recommended.  | |||||||||||||||||||||||||||||||||||
| In Vivo Formulation | 10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (8.69 mM), Sonication is recommended. Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
| ||||||||||||||||||||||||||||||||||||
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy Dihydroresveratrol | purchase Dihydroresveratrol | Dihydroresveratrol cost | order Dihydroresveratrol | Dihydroresveratrol chemical structure | Dihydroresveratrol formula | Dihydroresveratrol molecular weight
Generate Quote
Catalog No.: Cas No.:
Add
| Size | Quantity | Unit Price | Amount | Operation |
|---|
Generate Quote
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.