Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Dacomitinib hydrate (PF 299804) is a highly selective and second-generation small-molecule inhibitor of the pan-epidermal growth factor receptor family of tyrosine kinases. Dacomitinib specifically and irreversibly binds to and inhibits human EGFR subtypes, resulting in inhibition of proliferation and induction of apoptosis in EGFR-expressing tumor cells.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 31.00 | |
2 mg | In stock | $ 44.00 | |
5 mg | In stock | $ 72.00 | |
10 mg | In stock | $ 122.00 | |
25 mg | In stock | $ 179.00 | |
50 mg | In stock | $ 239.00 | |
100 mg | In stock | $ 372.00 | |
500 mg | In stock | $ 869.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 91.00 |
Description | Dacomitinib hydrate (PF 299804) is a highly selective and second-generation small-molecule inhibitor of the pan-epidermal growth factor receptor family of tyrosine kinases. Dacomitinib specifically and irreversibly binds to and inhibits human EGFR subtypes, resulting in inhibition of proliferation and induction of apoptosis in EGFR-expressing tumor cells. |
Synonyms | PF 299804, PF00299804, PF 00299804, PF-00299804, PF299804, PF-299804 |
Molecular Weight | 487.96 |
Formula | C24H27ClFN5O3 |
CAS No. | 1042385-75-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 55 mg/ml (112.71 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Dacomitinib hydrate 1042385-75-0 Angiogenesis JAK/STAT signaling Tyrosine Kinase/Adaptors EGFR PF 299804 PF00299804 PF 00299804 PF-00299804 Dacomitinib Hydrate PF299804 PF-299804 inhibitor inhibit