Powder: -20°C for 3 years
In solvent: -80°C for 2 years
Dexpanthenol is an alcoholic analogue of D-pantothenic acid and cholinergic agent. Dexpanthenol acts as a precursor of coenzyme A necessary for acetylation reactions and is involved in the synthesis of acetylcholine. Although the exact mechanism of the actions of dexpanthenol is unclear, it may enhance the effect of acetylcholine. Dexpanthenol acts on the gastrointestinal tract and increases lower intestinal motility. It is also applied topically to the skin to relieve itching and to promote healing.
Description | Dexpanthenol is an alcoholic analogue of D-pantothenic acid and cholinergic agent. Dexpanthenol acts as a precursor of coenzyme A necessary for acetylation reactions and is involved in the synthesis of acetylcholine. Although the exact mechanism of the actions of dexpanthenol is unclear, it may enhance the effect of acetylcholine. Dexpanthenol acts on the gastrointestinal tract and increases lower intestinal motility. It is also applied topically to the skin to relieve itching and to promote healing. |
In vivo | Dexpanthenol has positive effects on protection of cerebral tissue after ischaemia reperfusion[1]. Topical application of dexpanthenol is widely used in clinical practice for the improvement of wound healing. Upregulation of IL-6, IL-1, CYP1B1, CXCL1, CCL18 and KAP 4-2 gene expression and downregulation of psorasin mRNA and protein expression are identified in samples treated topically with dexpanthenol[2]. |
Synonyms | D-Pantothenyl alcohol, Ilopan, Dexpanthenol, Pantothenol |
Molecular Weight | 205.25 |
Formula | C9H19NO4 |
CAS No. | 81-13-0 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
DMSO: 33 mg/mL (160.78 mM), Need ultrasonic and warming
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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D-Panthenol 81-13-0 Metabolism Endogenous Metabolite DPanthenol Inhibitor D-Pantothenyl alcohol Ilopan Dexpanthenol Pantothenol D Panthenol inhibit inhibitor