Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Chlortetracycline Hydrochloride is a tetracycline with broad-spectrum antibacterial and antiprotozoal activity. Chlortetracycline hydrochloride (Isphamycin) is bacteriostatic and inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit, thereby preventing the addition of amino acids to the growing peptide chain. This tetracycline is active against a wide range of gram-positive and gram-negative organisms, spirochetes, rickettsial species, certain protozoa and Mycoplasma and Chlamydia organisms.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
100 mg | In stock | $ 30.00 | |
200 mg | In stock | $ 45.00 | |
250 mg | In stock | $ 50.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 45.00 |
Description | Chlortetracycline Hydrochloride is a tetracycline with broad-spectrum antibacterial and antiprotozoal activity. Chlortetracycline hydrochloride (Isphamycin) is bacteriostatic and inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit, thereby preventing the addition of amino acids to the growing peptide chain. This tetracycline is active against a wide range of gram-positive and gram-negative organisms, spirochetes, rickettsial species, certain protozoa and Mycoplasma and Chlamydia organisms. |
In vivo | Chlortetracycline HCl exhibits inhibitory activity against a range of organisms, including Diplococcus pneumoniae (MIC: 0.098 mg/L), Streptococcus pyogenes (MIC: 0.292 mg/L), two strains of Bacillus subtilis (MICs: 0.195 mg/L and 0.15 mg/L), Streptococcus faecalis (MIC: 0.3 mg/L), and Mycobacterium ranae (0.3 mg/L). Its high affinity to a site on the 30S subunit effectively suppresses the activity of various Gram-positive and Gram-negative bacteria, including obligatory anaerobes. |
Synonyms | Isphamycin, Chlortetracycline HCl, 7-Chlorotetracycline hydrochloride |
Molecular Weight | 515.35 |
Formula | C22H23ClN2O8·HCl |
CAS No. | 64-72-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 10 mg/mL (19.4 mM)
H2O: 10 mg/mL (19 mM)
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Chlortetracycline hydrochloride 64-72-2 Microbiology/Virology ribosome Antibacterial Antibiotic Bacterial inhibit Isphamycin Chlortetracycline HCl Inhibitor 7-Chlorotetracycline hydrochloride 7-Chlorotetracycline Hydrochloride Chlortetracycline 7-Chlorotetracycline Chlortetracycline Hydrochloride inhibitor