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Chlorhexidine

Catalog No. T1000 CAS 55-56-1

Synonyms: Rotersept, Chlorhexidinum, Nolvasan, 氯己定

Chlorhexidine is a biguanide compound used as an antiseptic agent with topical antibacterial activity. Chlorhexidine is positively charged and reacts with the negatively charged microbial cell surface, thereby destroying the integrity of the cell membrane. Subsequently, chlorhexidine penetrates into the cell and causes leakage of intracellular components leading to cell death. Since gram-positive bacteria are more negatively charged, they are more sensitive to this agent.

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Chlorhexidine, CAS 55-56-1

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	Rotersept, Chlorhexidinum, Nolvasan, 氯己定
Molecular Weight	505.45
Formula	C22H30Cl2N10
CAS No.	55-56-1

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: 91 mg/mL(180 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Solov'eva NN, et al. Antibiotiki. 1979 Jun;24(6):436-40. 2. Dong L, Shen S, Chen W, et al. Discovery of Novel Inhibitors Targeting Human O-GlcNAcase: Docking-Based Virtual Screening, Biological Evaluation, Structural Modification, and Molecular Dynamics Simulation[J]. Journal of chemical information and modeling. 2019, 59(10): 4374-4382.

Citations

1. Dong L, Shen S, Chen W, et al. Discovery of Novel Inhibitors Targeting Human O-GlcNAcase: Docking-Based Virtual Screening, Biological Evaluation, Structural Modification, and Molecular Dynamics Simulation. Journal of chemical information and modeling. 2019, 59(10): 4374-4382.

Related compound libraries

This product is contained In the following compound libraries：

Anti-Cancer Compound Library Antibiotics Library Inhibitor Library Oxidation-Reduction Compound Library Drug Repurposing Compound Library Anti-Cancer Approved Drug Library FDA-Approved Drug Library Approved Drug Library Anti-Cancer Drug Library FDA-Approved & Pharmacopeia Drug Library

Related Products

Related compounds with same targets

Protoanemonin (-)-α-Pinene Beta-mangostin Nanchangmycin Amikacin hydrate Sulfaclozine sodium Lenampicillin hydrochloride Cephradine monohydrate

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Chlorhexidine 55-56-1 微生物学氧化还原 Antibacterial Antibiotic Antifection CAT Inhibitor Nolvasan inhibit Bacterial Rotersept Chlorhexidinum inhibitor

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