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Home > Microbiology&virology > Antifection > Chlorhexidine

Chlorhexidine

Catalog No. T1000    CAS 55-56-1    Synonyms: Chlorhexidinum, Nolvasan, Rotersept

Chlorhexidine is a biguanide compound used as an antiseptic agent with topical antibacterial activity. Chlorhexidine is positively charged and reacts with the negatively charged microbial cell surface, thereby destroying the integrity of the cell membrane. Subsequently, chlorhexidine penetrates into the cell and causes leakage of intracellular components leading to cell death. Since gram-positive bacteria are more negatively charged, they are more sensitive to this agent.

Pack Size Availability Price/USD Quantity
100 mg In stock 52.00
200 mg In stock 89.00
1 mL * 10 mM (in DMSO) In Stock 50.00
Bulk Size: Please Quote for Discount Please Quote for Bulk Size
Biological Activity:

Product Description:

Chlorhexidine is a biguanide compound used as an antiseptic agent with topical antibacterial activity. Chlorhexidine is positively charged and reacts with the negatively charged microbial cell surface, thereby destroying the integrity of the cell membrane. Subsequently, chlorhexidine penetrates into the cell and causes leakage of intracellular components leading to cell death. Since gram-positive bacteria are more negatively charged, they are more sensitive to this agent.

Receptor:

CAT; HNMT;

Chemical Information:
Molecular Weight 505.45
Formula C22H30Cl2N10
CAS Number 55-56-1
Solubility

DMSO: 91 mg/mL (180 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage store at -80°C
Remark For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ℃ for several month.
Technical Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.

Reference
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