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Calcifediol monohydrate (Synonyms: 25-hydroxy Vitamin D3 monohydrate)

Name: Calcifediol monohydrate
Brand: TargetMol
SKU: T6430L
Price: 39 USD
Availability: InStock
Rating: 5 (10 reviews)

Catalog No. T6430L Copy Product Info

Purity: 99.31%

🥰Excellent

Calcifediol monohydrate (25-hydroxy Vitamin D3 monohydrate), the primary circulating metabolite of Vitamin D3, serves as a potent VDR inhibitor.

Calcifediol monohydrate

Copy Product Info

🥰Excellent

Catalog No. T6430L

Synonyms 25-hydroxy Vitamin D3 monohydrate

Calcifediol monohydrate (25-hydroxy Vitamin D3 monohydrate), the primary circulating metabolite of Vitamin D3, serves as a potent VDR inhibitor.

Cas No. 63283-36-3

Pack Size	Price	USA Stock	Global Stock
1 mg	$39	In Stock	In Stock
5 mg	$89	In Stock	In Stock
10 mg	$147	In Stock	In Stock
25 mg	$297	In Stock	In Stock
50 mg	$479	-	In Stock
100 mg	$737	-	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Batch Information

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Purity:99.31%

Appearance:Solid

Color:White

Resource Download

COA HNMR ORP LCMS

Product Introduction

Bioactivity

Description	Calcifediol monohydrate (25-hydroxy Vitamin D3 monohydrate), the primary circulating metabolite of Vitamin D3, serves as a potent VDR inhibitor.
Synonyms	25-hydroxy Vitamin D3 monohydrate

Chemical Properties

Molecular Weight	418.65
Formula	C₂₇H₄₆O₃
Cas No.	63283-36-3
Smiles	C[C@@]12[C@](\C(=C\C=C\3/C(=C)CC[C@H](O)C3)\CCC1)(CC[C@@]2([C@@H](CCCC(C)(C)O)C)[H])[H].O
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: insoluble

DMSO: 60 mg/mL (143.32 mM), Sonication is recommended.

Ethanol: 120 mg/mL (286.64 mM), Sonication is recommended.

Solution Preparation Table

DMSO/Ethanol

	1mg	5mg	10mg	50mg
1 mM	2.3886 mL	11.9432 mL	23.8863 mL	119.4315 mL
5 mM	0.4777 mL	2.3886 mL	4.7773 mL	23.8863 mL
10 mM	0.2389 mL	1.1943 mL	2.3886 mL	11.9432 mL
20 mM	0.1194 mL	0.5972 mL	1.1943 mL	5.9716 mL
50 mM	0.0478 mL	0.2389 mL	0.4777 mL	2.3886 mL
100 mM	0.0239 mL	0.1194 mL	0.2389 mL	1.1943 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc