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TargetMol | Compound Library

Orally Active Compound Library

Catalog No. L9850

Oral administration is the first choice for clinical drug delivery, especially for long-term use. It is also the safest, most convenient, and most economical method of drug delivery. Oral bioavailability is the percentage of the absorbed drug dose successfully passed through the mucosa of the gastrointestinal tract and entered the bloodstream through the liver, to the original given oral dose. Drugs with high oral bioavailability can achieve efficacy at lower doses and effectively reduce toxic side effects; while when bioavailability is too low, even compounds with good pharmacological activity are unable to be fully exposed and utilized at the target site, resulting in therapeutic failure or high dose with large toxic side effects, which eventually leads to drug development failure and limits the application.
TargetMol has carefully collected 3160 compounds with publicly reported oral activity that can be used for drug repurposing and development of orally active drugs.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L9850

Orally Active Compound Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 3160 of orally active compounds for high-throughput screening and high-content screening.
  • Some drugs are approved or are in clinical trials with validated biological activity and safety.
  • Detailed specifications, compound structures, target information, activity descriptions, etc.
  • NMR and HPLC detection techniques to ensure high product purity.
  • All compounds are available in stock.

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

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Library Customization | TargetMol Library Composition

Apoptosis
Autophagy
Antibacterial
Antibiotic
Endogenous Metabolite
5-HT Receptor
Adrenergic Receptor
Dopamine Receptor
Histamine Receptor
Parasite
COX
DNA/RNA Synthesis
AChR
HIV Protease
Potassium Channel
VEGFR
ROS
EGFR
Calcium Channel
NF-κB
Cytochromes P450
Sodium Channel
SARS-CoV
PDE
CDK
PDGFR
p38 MAPK
Estrogen/progestogen Receptor
Dehydrogenase
Reactive Oxygen Species
FLT
Glucocorticoid Receptor
c-Kit
Virus Protease
PI3K
Estrogen Receptor/ERR
RAAS
Akt
Antifungal
JAK
HCV Protease
Ferroptosis
ERK
Topoisomerase
Src
Mitophagy
iGluR
Ras
HBV
FGFR
Microtubule Associated
c-Met/HGFR
PPAR
Serotonin Transporter
Interleukin
Influenza Virus
GABA Receptor
Reverse Transcriptase
HDAC
Proteasome
Prostaglandin Receptor
TNF
TRP/TRPV Channel
Bcr-Abl
mTOR
GPCR
GluR
Phosphatase
Caspase
Androgen Receptor
Raf
Epigenetic Reader Domain
Beta Amyloid
STAT
Histone Methyltransferase
Nucleoside Antimetabolite/Analog
HSV
MMP
Norepinephrine
MAPK
ALK
LPL Receptor
Adenosine Receptor
Progesterone Receptor
Tyrosine Kinases
Transferase
PARP
Mitochondrial Metabolism
Cholinesterase (ChE)
P-gp
NO Synthase
Monoamine Oxidase
GSK-3
Angiotensin-converting Enzyme (ACE)
HIF/HIF Prolyl-Hydroxylase
Integrin
Wnt/beta-catenin
HSP
Bcl-2 Family
MEK
Proton pump
Opioid Receptor
DPP-4
Antiviral
c-Fms
Thrombin
Kras
Drug Metabolite
Trk receptor
ribosome
HER
S1P Receptor
Reductase
JNK
Factor Xa
NMDAR
TLR
Retinoid Receptor
AMPK
Carbonic Anhydrase
Leukotriene Receptor
ROCK
Lipoxygenase
Phospholipase
c-RET
Syk
ROS Kinase
PKC
MAO
Endothelin Receptor
Aurora Kinase
IGF-1R
TGF-beta/Smad
Acyltransferase
MDM-2/p53
TAM Receptor
ATPase
NADPH
PERK
Glutathione Peroxidase
MRP
Serine Protease
Gamma-secretase
CCR
CXCR
SGLT
ATM/ATR
Cannabinoid Receptor
Thyroid hormone receptor(THR)
DHFR
PKA
E1/E2/E3 Enzyme
Isocitrate Dehydrogenase (IDH)
Fatty Acid Synthase
IL Receptor
Nrf2
RSV
Anti-infection
CSF-1R
DNA gyrase
Antifection
Molecular Glues
Complement System
IRAK
HMG-CoA Reductase
CFTR
BTK
ROR
Histone Demethylase
Serine/threonin kinase
Glucagon Receptor
P2X Receptor
Guanylate cyclase
Hedgehog/Smoothened
Xanthine Oxidase
Ligand for E3 Ligase
Neurokinin receptor
Antioxidant
DNA Alkylator/Crosslinker
Cysteine Protease
FXR
ABC Transporter
Vasopressin Receptor
glycosidase
CaMK
Beta-Secretase
Casein Kinase
IκB/IKK
Hydroxylase
PLK
FAK
NOD-like Receptor (NLR)
P2Y Receptor
LTR
Antifolate
IDO
Stearoyl-CoA Desaturase (SCD)
OX Receptor
Chk
Indoleamine 2,3-Dioxygenase (IDO)
Aminopeptidase
transporter
Aromatase
GHSR
HIF
DNA Methyltransferase
PD-1/PD-L1
PROTACs
Amino Acids and Derivatives
YAP
Lipase
GNRH Receptor
Pim
Aryl Hydrocarbon Receptor
IAP
Glucosidase
Smo
DNA Alkylation
OXPHOS
Ephrin Receptor
ASK
PAI-1
Sigma receptor
ADC Cytotoxin
IKZF
Mdm2
NOS
DNA-PK
CRM1
BACE
IFNAR
Melatonin Receptor
LDLR
RIP kinase
MAGL
PAK
Thrombopoietin Receptor
Telomerase
PGE Synthase
Porcupine
Histone Acetyltransferase
NADPH-oxidase
p53
Monocarboxylate transporter
MTP
Cholecystokinin Receptor
Vitamin
FLAP
UGT
MT Receptor
GlyT
Monoamine Transporter
Neuropeptide Y Receptor
FAAH
DNA
DUB
Sirtuin
Neprilysin
GST
Oxytocin Receptor
S6 Kinase
Protease-activated Receptor
AhR
MicroRNA
Necroptosis
Tie-2
TOPK
c-Myc
CaSR
Glucokinase
Glutaminase
Annexin A
PAFR
Hexokinase
Bradykinin Receptor
PAD
Epoxide Hydrolase
BCRP
OAT
Survivin
Free radical scavengers
Acetyl-CoA Carboxylase
FKBP
LPA Receptor
PI4K
FOXO
SGK
Discoidin Domain Receptor (DDR)
NOD
MLK
Melanin-concentrating Hormone Receptor (MCHR)
Advanced Glycation End Products
MALT
NEDD8
Ligands for Target Protein for PROTAC
Cell wall
OCT
Galectin
Rho
Hck
ATG
Liver X Receptor
Neurotensin Receptor
NR4A
Immunology/Inflammation related
SIK
IRE1
LDL
Na-K-Cl cotransporter
Integrase
PROTAC Linker
Mucin
ATP Citrate Lyase
Wee1
Lipid
MNK
STING
LRRK2
GPCR19
GluCls
Hippo pathway
Melanocortin Receptor
PDK
Adenosine Deaminase
CGRP Receptor
Cuproptosis
Gap Junction Protein
Platelet aggregation
BMI-1
Tyrosinase
Imidazoline Receptor
Kinesin
Chloride channel
Taste receptor
GSNOR
NPC1L1
Hydrogenase
CD38
ASBT
Arginase
Na+/Ca2+ Exchanger
DYRK
MIF
GTPase
AAK1
NAMPT
PYK2
Prolyl Endopeptidase (PREP)
Myosin
Adiponectin Receptor
Haspin Kinase
GRK
PACAP
AAK1 (AP2 associated kinase 1)
Arp2/3 Complex
HCN Channel
ACK1
HCAR
PTEN
Somatostatin
cAMP
Glutathione reductase
Urea Transporter
Decarboxylase
Pyroptosis
Methionine Adenosyltransferase (MAT)
p62
GPX
CRISPR/Cas9
RXFP receptor
DAPK
p97
PKM
Ferroportin
Sodium-dependent phosphate transporter
PGC-1α

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