Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CEP-37440 is an effective and specific Dual FAK/ALK inhibitor with IC50s of 120 nM(ALK cellular in 75% human plasma) and 2.3 nM (FAK).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 31.00 | |
2 mg | In stock | $ 44.00 | |
5 mg | In stock | $ 72.00 | |
10 mg | In stock | $ 128.00 | |
25 mg | In stock | $ 269.00 | |
50 mg | In stock | $ 513.00 | |
100 mg | In stock | $ 746.00 |
Description | CEP-37440 is an effective and specific Dual FAK/ALK inhibitor with IC50s of 120 nM(ALK cellular in 75% human plasma) and 2.3 nM (FAK). |
Targets&IC50 | FAK:2.3 nM, ALK:120 nM |
Kinase Assay | Kinase assay: Inhibitory potency of GSK2656157 is measured using recombinant GST-PERK (536–1116 amino acids) with 6-His-full-length human eIF2a as a substrate. Kinase selectivity is evaluated using 27 kinases at GSK as well as a panel of 300 kinases. |
Synonyms | CEP37440 |
Molecular Weight | 580.12 |
Formula | C30H38ClN7O3 |
CAS No. | 1391712-60-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 2.2 mg/mL (3.79 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
CEP-37440 1391712-60-9 Angiogenesis Cytoskeletal Signaling Tyrosine Kinase/Adaptors ALK FAK inhibit Inhibitor CEP 37440 Cluster of differentiation 246 PTK2 triple-negative breast cancer inflammatory breast cancer Anaplastic lymphoma kinase FAK1 Anaplastic lymphoma kinase (ALK) Focal adhesion kinase CEP37440 PTK2 protein tyrosine kinase 2 autophosphorylation kinase CD246 ALK tyrosine kinase receptor inhibitor