Powder: -20°C for 3 years | In solvent: -80°C for 1 year
C-82 is a specific CBP/β-catenin antagonist. It inhibits the binding between β-catenin and CBP and increases the binding between β-catenin and p300.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 453.00 | |
5 mg | In stock | $ 913.00 | |
10 mg | In stock | $ 1,319.00 | |
25 mg | In stock | $ 2,090.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 1,190.00 |
Description | C-82 is a specific CBP/β-catenin antagonist. It inhibits the binding between β-catenin and CBP and increases the binding between β-catenin and p300. |
In vitro | C-82 inhibits the activation of isolated primary mouse quiescent hepatic stellate cells (HSCs) and promotes cell death in culture-activated HSCs. |
In vivo | PRI-724 is phosphorylated-C-82 and is rapidly hydrolyzed to its active form C-82 in vivo, and pre-clinical studies have shown a very acceptable toxicity profile. |
Molecular Weight | 578.66 |
Formula | C33H34N6O4 |
CAS No. | 1422253-37-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 55 mg/ml (95.05 mM)
You can also refer to dose conversion for different animals. More
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C-82 1422253-37-9 Chromatin/Epigenetic Cytoskeletal Signaling Stem Cells Epigenetic Reader Domain Wnt/beta-catenin C 82 C82 inhibitor inhibit