Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Apomine (SR-9223i), an inhibitor of HMG-CoA-reductase, promotes apoptosis of myeloma cells in vitro and has been implicated in the regulation of myeloma in vivo. Apomine accelerates the degradation of 3-hydroxy-3-methylglutaryl-CoA reductase and stimulates low-density lipoprotein receptor activity. Apomine enhances the antitumor effect of lovastatin on myeloma cells by downregulating 3-hydroxy-3-methylglutaryl-CoA reductase.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 148.00 | |
5 mg | In stock | $ 336.00 | |
10 mg | In stock | $ 497.00 | |
25 mg | In stock | $ 793.00 | |
50 mg | In stock | $ 1,130.00 | |
100 mg | In stock | $ 1,520.00 | |
500 mg | In stock | $ 2,970.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 438.00 |
Description | Apomine (SR-9223i), an inhibitor of HMG-CoA-reductase, promotes apoptosis of myeloma cells in vitro and has been implicated in the regulation of myeloma in vivo. Apomine accelerates the degradation of 3-hydroxy-3-methylglutaryl-CoA reductase and stimulates low-density lipoprotein receptor activity. Apomine enhances the antitumor effect of lovastatin on myeloma cells by downregulating 3-hydroxy-3-methylglutaryl-CoA reductase. |
Synonyms | SK&F-99085, APB-231-A2, APB-231-A-2, SR-9223i, SK&F-99085, SR-45023A |
Molecular Weight | 562.66 |
Formula | C28H52O7P2 |
CAS No. | 126411-13-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 15 mg/ml (26.66 mM)
You can also refer to dose conversion for different animals. More
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Apomine 126411-13-0 Metabolism HMG-CoA Reductase SK&F 99085 SK&F-99085 SK&F99085 APB-231-A2 APB-231-A-2 SK&F99085 SR-9223i SK&F-99085 SR-45023A SK&F 99085 inhibitor inhibit