Powder: -20°C for 3 years | In solvent: -80°C for 1 year
5-OHdU (5-OHdU) is a major oxidation product of 2'-Deoxycytidine and can be incorporated into DNA in vitro.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 39.00 | |
2 mg | In stock | $ 55.00 | |
5 mg | In stock | $ 91.00 | |
10 mg | In stock | $ 133.00 | |
25 mg | In stock | $ 223.00 | |
50 mg | In stock | $ 333.00 | |
100 mg | In stock | $ 498.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 92.00 |
Description | 5-OHdU (5-OHdU) is a major oxidation product of 2'-Deoxycytidine and can be incorporated into DNA in vitro. |
In vitro | Translesion synthesis past 5-OHdU in 18- and 45-member oligodeoxyribonucleotides occurred, but pauses both opposite, and one nucleotide prior to, the modified base in the template is observed. The specificity of nucleotide incorporation opposite 5-OHdU in the template is sequence context-dependent. In one sequence context, dA is the principal nucleotide incorporated opposite 5-OHdU. However, in a second sequence context, dC is the predominant base incorporated opposite 5-OHdU. In that same sequence context, dC is also the predominant nucleotide incorporated opposite 5-OHdU[1]. |
Synonyms | 5-OHdU |
Molecular Weight | 244.2 |
Formula | C9H12N2O6 |
CAS No. | 5168-36-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 30 mg/mL (122.9 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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5-OHdU 5168-36-5 Cell Cycle/Checkpoint DNA Damage/DNA Repair Metabolism Nucleoside Antimetabolite/Analog Endogenous Metabolite inhibitor inhibit