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5-ALA benzyl ester hydrochloride
🥰Excellent
Catalog No. T19147Cas No. 163271-32-7
Alias Benzyl-ALA hydrochloride
5-ALA benzyl ester hydrochloride (Benzyl-ALA hydrochloride) is a protoporphyrin precursor used as a photodetection agent. It induces protoporphyrin IX (PPIX) accumulation in colon carcinoma cell lines.
5-ALA benzyl ester hydrochloride
🥰Excellent
Purity: 98.72%
Catalog No. T19147Alias Benzyl-ALA hydrochlorideCas No. 163271-32-7
5-ALA benzyl ester hydrochloride (Benzyl-ALA hydrochloride) is a protoporphyrin precursor used as a photodetection agent. It induces protoporphyrin IX (PPIX) accumulation in colon carcinoma cell lines.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | $31 | In Stock | |
| 10 mg | $51 | In Stock | |
| 25 mg | $84 | In Stock | |
| 50 mg | $123 | In Stock | |
| 100 mg | $182 | In Stock | |
| 200 mg | $269 | In Stock | |
| 500 mg | $456 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $57 | In Stock |
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Purity:98.72%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | 5-ALA benzyl ester hydrochloride (Benzyl-ALA hydrochloride) is a protoporphyrin precursor used as a photodetection agent. It induces protoporphyrin IX (PPIX) accumulation in colon carcinoma cell lines. |
| In vitro | In colon carcinoma cell lines SW480, 5-ALA benzyl ester hydrochloride (0.6-0.12 mM; 3h) induces PPIX accumulation[1]. |
| In vivo | In female CBA/Gy mice, 5-ALA benzyl ester hydrochloride (31 mg/kg; i.v.; 1h) results in a dose-dependent reduction in tumour porphyrin levels[2]. |
| Animal Research | Animal Model: Female CBA/Gy mouse (CaNT tumour model)
Dosage: 31 mg/kg Administration: i.v. ; 1 hours [3] |
| Alias | Benzyl-ALA hydrochloride |
| Molecular Weight | 257.71 |
| Formula | C12H16ClNO3 |
| Cas No. | 163271-32-7 |
| Smiles | Cl.NCC(=O)CCC(=O)OCc1ccccc1 |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 245 mg/mL (950.68 mM), Sonication is recommended. H2O: 95 mg/mL (368.63 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
H2O/DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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