Powder: -20°C for 3 years | In solvent: -80°C for 1 year
1, 5-Isoquinolinediol is an inhibitor of poly(ADP-ribose) synthetase (PARP1; IC50: 0.39 μM). The poly(ADP-ribose) polymerases (PARPs) form a family of enzymes with roles in DNA repair and apoptosis. 1, 5-Isoquinolinediol has been used to study the role of PARP1 in both DNA repair and oxidant stress-induced cell death. This compound can be used with cells in culture and in animals.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 58.00 | |
10 mg | In stock | $ 87.00 | |
50 mg | In stock | $ 191.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 58.00 |
Description | 1, 5-Isoquinolinediol is an inhibitor of poly(ADP-ribose) synthetase (PARP1; IC50: 0.39 μM). The poly(ADP-ribose) polymerases (PARPs) form a family of enzymes with roles in DNA repair and apoptosis. 1, 5-Isoquinolinediol has been used to study the role of PARP1 in both DNA repair and oxidant stress-induced cell death. This compound can be used with cells in culture and in animals. |
Targets&IC50 | PARP1:0.39 μM |
Molecular Weight | 161.16 |
Formula | C9H7NO2 |
CAS No. | 5154-02-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 1 mg/mL
Ethanol: 20 mg/mL
DMSO: 55 mg/mL (341.28 mM)
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
1,5-Isoquinolinediol 5154-02-9 Chromatin/Epigenetic DNA Damage/DNA Repair PARP diabetic 1188540 oxidative retinopathy 1,5 Isoquinolinediol stress inhibit NADPH Inhibitor 1,5Isoquinolinediol oxidase poly ADP ribose polymerase inhibitor