Powder: -20°C for 3 years | In solvent: -80°C for 1 year
(R)-5-Oxopyrrolidine-2-carboxylic acid (D-Pyroglutamic acid) is a cyclic derivative of glutamic acid, physiologically present in mammalian tissues. It has been shown that PCA releases GABA from the cerebral cortex and displays anti-anxiety effects in a simple approach-avoidance conflict situation in the rat. In clinical pharmacology experiments, PCA significantly shortens the plasma half-life of ethanol during acute intoxication.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
500 mg | In stock | $ 64.00 | |
1 g | In stock | $ 91.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 45.00 |
Description | (R)-5-Oxopyrrolidine-2-carboxylic acid (D-Pyroglutamic acid) is a cyclic derivative of glutamic acid, physiologically present in mammalian tissues. It has been shown that PCA releases GABA from the cerebral cortex and displays anti-anxiety effects in a simple approach-avoidance conflict situation in the rat. In clinical pharmacology experiments, PCA significantly shortens the plasma half-life of ethanol during acute intoxication. |
Synonyms | D-Pyroglutamic acid, (R)-(+)-2-Pyrrolidone-5-carboxylic acid |
Molecular Weight | 129.11 |
Formula | C5H7NO3 |
CAS No. | 4042-36-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 55 mg/mL (425.99 mM)
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
(R)-5-Oxopyrrolidine-2-carboxylic acid 4042-36-8 Metabolism Others Endogenous Metabolite 5-Oxopyrrolidine-2-carboxylic acid Inhibitor (R) 5 Oxopyrrolidine 2 carboxylic acid D-Pyroglutamic acid 2-Pyrrolidone-5-carboxylic acid (R)5Oxopyrrolidine2carboxylic acid (R)-(+)-2-Pyrrolidone-5-carboxylic acid inhibit inhibitor