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Search Results for " unwinding "

2

Compounds

Cat No. Product Name Synonyms Targets
T5413 ML216 CID-49852229 DNA/RNA Synthesis
ML216 (CID-49852229) is a small molecule inhibitor of BLM helicase (IC50: 1.8 μM). It showed 28-fold selective against the related helicases RECQ1, RECQ5, and E. coli UvrD (IC50s > 50 μM).
T0486 Irinotecan hydrochloride trihydrate Irinotecan HCl Trihydrate,CPT-11 HCl Trihydrate Topoisomerase , Autophagy
Irinotecan hydrochloride trihydrate (CPT-11 HCl Trihydrate) keeps DNA from unwinding by inhibiting topoisomerase 1.
TargetMol