2
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T5413 | ML216 | CID-49852229 | DNA/RNA Synthesis |
ML216 (CID-49852229) is a small molecule inhibitor of BLM helicase (IC50: 1.8 μM). It showed 28-fold selective against the related helicases RECQ1, RECQ5, and E. coli UvrD (IC50s > 50 μM). | |||
T0486 | Irinotecan hydrochloride trihydrate | Irinotecan HCl Trihydrate,CPT-11 HCl Trihydrate | Topoisomerase , Autophagy |
Irinotecan hydrochloride trihydrate (CPT-11 HCl Trihydrate) keeps DNA from unwinding by inhibiting topoisomerase 1. |