15
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T3185 | R112 | (E)-Elafibranor | Syk |
R112 ((E)-Elafibranor) is an ATP-competitive inhibitor of Syk kinase. | |||
T8362 | Benzamidine hydrochloride | Benzamidine HCl | Serine/threonin kinase , Serine Protease |
Benzamidine hydrochloride (Benzamidine HCl) is a reversible inhibitor of serine proteases, including trypsin, plasmin, and thrombin (Ki of 35, 350, and 220 μM, respectively). | |||
T38052 | CRA-2059 TFA | ||
CRA-2059 is a highly specific and selective tryptase inhibitor, with a Ki of 620 pM for recombinant human tryptase-β (rHTβ)[1][2]. Tryptase is a trypsin-like serine protease found as a major protein component in human ma... | |||
T70193 | APC-366 HCl | ||
APC-366 is a selective inhibitor of the mast cell tryptase that inhibits tryptase-induced histamine release from human tonsil and lung cells. | |||
T40195 | CRA-2059 | ||
CRA-2059 is a potent and selective inhibitor of tryptase, particularly targeting recombinant human tryptase-β (rHTβ), with a K i of 620 pM. | |||
T38051 | CRA-2059 hydrochloride | ||
CRA-2059 hydrochloride is a highly specific and selective tryptase inhibitor, with a Ki of 620 pM for recombinant human tryptase-β (rHTβ)[1][2]. Tryptase is a trypsin-like serine protease found as a major protein compone... | |||
T71585 | DB03417 | ||
DB03417 is a compound listed in web page: https://go.drugbank.com/drugs/DB03417. DB03417 is a potential tryptase inhibitor. | |||
T80107 | Tos-Gly-Pro-Lys-AMC | ||
Tos-Gly-Pro-Lys-AMC is a fluorogenic peptide substrate that is specific for tryptase [1]. | |||
T40081 | APC 366 TFA | ||
APC 366 (TFA) is a potent irreversible inhibitor of mast cell tryptase. It is particularly useful in studies related to allergic diseases. | |||
T77221 | Benzenecarboximidamide, hydrochloride, hydrate (1:1:x) | ||
Benzenecarboximidamide, hydrochloride, hydrate (1:1:x) (Benzamidine hydrochloride hydrate) is a reversible competitive trypsin-like serine proteases inhibitor with K i s of 20, 21, 97, 110, 320 and 750 μM against Tryptas... | |||
T22189 | APC 366 | ||
APC 366 is a selective inhibitor of mast cell tryptase with Ki of 7.1 μM. APC 366 inhibits antigen-induced early asthmatic response (EAR), late asthmatic response (LAR), and bronchial hyperresponsiveness (BHR) in a sheep... | |||
T39029 | APC-6860 | ||
APC-6860 is a trypsin-like serine proteases inhibitor with k i values of 0.21, 0.44, 1.5, 16.8, 20, 30 μM for uPA, trypsin, tryptase, tPA, thrombin and factor Xa, respectively. APC-6860 has a selectivity ratio for tPA ve... | |||
T11269 | FD-IN-1 | Others | |
FD-IN-1 is a factor D (FD) inhibitor with an IC50 of 12 nM.FD-IN-1 also inhibits factor XIa (FXIa) and Tryptase β2 with IC50s of 7.7 and 6.5μM, respectively. Complement FD, a highly specific S1 serine protease, plays a... | |||
T68474 | RWJ-58643 HCl | ||
RWJ 58643 is a reversible beta-tryptase and trypsin inhibitor. Low-dose RWJ-58643 (100 microg) and budesonide (200 microg) significantly reduced symptoms, eosinophils and levels of IL-5 following NAC. However, higher dos... | |||
T30510 | BMS-262084 | BMS 262084,I0IR71971G,UNII-I0IR71971G,CHEMBL71037 | |
BMS-262084 is a potent selective β-lactam trypsin inhibitor with therapeutic potential in the treatment of asthma. |