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Search Results for " tryptase "

15

Compounds

Cat No. Product Name Synonyms Targets
T3185 R112 (E)-Elafibranor Syk
R112 ((E)-Elafibranor) is an ATP-competitive inhibitor of Syk kinase.
T8362 Benzamidine hydrochloride Benzamidine HCl Serine/threonin kinase , Serine Protease
Benzamidine hydrochloride (Benzamidine HCl) is a reversible inhibitor of serine proteases, including trypsin, plasmin, and thrombin (Ki of 35, 350, and 220 μM, respectively).
T38052 CRA-2059 TFA
CRA-2059 is a highly specific and selective tryptase inhibitor, with a Ki of 620 pM for recombinant human tryptase-β (rHTβ)[1][2]. Tryptase is a trypsin-like serine protease found as a major protein component in human ma...
T70193 APC-366 HCl
APC-366 is a selective inhibitor of the mast cell tryptase that inhibits tryptase-induced histamine release from human tonsil and lung cells.
T40195 CRA-2059
CRA-2059 is a potent and selective inhibitor of tryptase, particularly targeting recombinant human tryptase-β (rHTβ), with a K i of 620 pM.
T38051 CRA-2059 hydrochloride
CRA-2059 hydrochloride is a highly specific and selective tryptase inhibitor, with a Ki of 620 pM for recombinant human tryptase-β (rHTβ)[1][2]. Tryptase is a trypsin-like serine protease found as a major protein compone...
T71585 DB03417
DB03417 is a compound listed in web page: https://go.drugbank.com/drugs/DB03417. DB03417 is a potential tryptase inhibitor.
T80107 Tos-Gly-Pro-Lys-AMC
Tos-Gly-Pro-Lys-AMC is a fluorogenic peptide substrate that is specific for tryptase [1].
T40081 APC 366 TFA
APC 366 (TFA) is a potent irreversible inhibitor of mast cell tryptase. It is particularly useful in studies related to allergic diseases.
T77221 Benzenecarboximidamide, hydrochloride, hydrate (1:1:x)
Benzenecarboximidamide, hydrochloride, hydrate (1:1:x) (Benzamidine hydrochloride hydrate) is a reversible competitive trypsin-like serine proteases inhibitor with K i s of 20, 21, 97, 110, 320 and 750 μM against Tryptas...
T22189 APC 366
APC 366 is a selective inhibitor of mast cell tryptase with Ki of 7.1 μM. APC 366 inhibits antigen-induced early asthmatic response (EAR), late asthmatic response (LAR), and bronchial hyperresponsiveness (BHR) in a sheep...
T39029 APC-6860
APC-6860 is a trypsin-like serine proteases inhibitor with k i values of 0.21, 0.44, 1.5, 16.8, 20, 30 μM for uPA, trypsin, tryptase, tPA, thrombin and factor Xa, respectively. APC-6860 has a selectivity ratio for tPA ve...
T11269 FD-IN-1 Others
FD-IN-1 is a factor D (FD) inhibitor with an IC50 of 12 nM.FD-IN-1 also inhibits factor XIa (FXIa) and Tryptase β2 with IC50s of 7.7 and 6.5μM, respectively. Complement FD, a highly specific S1 serine protease, plays a...
T68474 RWJ-58643 HCl
RWJ 58643 is a reversible beta-tryptase and trypsin inhibitor. Low-dose RWJ-58643 (100 microg) and budesonide (200 microg) significantly reduced symptoms, eosinophils and levels of IL-5 following NAC. However, higher dos...
T30510 BMS-262084 BMS 262084,I0IR71971G,UNII-I0IR71971G,CHEMBL71037
BMS-262084 is a potent selective β-lactam trypsin inhibitor with therapeutic potential in the treatment of asthma.
TargetMol