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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T10826 | CK-666 | HIV Protease , Microtubule Associated | |
CK-666 is a cell-permeable inhibitor of actin-related protein Arp2/3 complex. It binds to the Arp2/3 complex, stabilizes the inactive state of the complex, blocking the movement of the Arp2 and Arp3 subunits into the act... | |||
T60924 | Verosudil | AR-12286 | ROCK |
Verosudil (AR-12286) is a highly potent Rho kinase (ROCK) inhibitor with a Ki of 2 and 2 nM against ROCK1 and ROCK2, respectively. AR-12286 reverses steroid-induced intraocular pressure in mice by decreasing intraocular ... | |||
T3S2312 | Poncirin | Isosakuranetin-7-neohesperidoside | Apoptosis , Others |
1. Poncirin (Isosakuranetin-7-neohesperidoside) shows a significant in vitro inhibitory effect on the growth of the human gastric cancer cells, SGC-791, in a dose-dependent manner. 2. Poncirin prevents adipogenesis, enha... | |||
T37955 | Sphingosine-1-phosphate (d16:1) | Sphingosine-1-phosphate (d16:1) | |
C16 Sphingosine-1-phosphate (C16 S1P) is a derivative of sphingosine-1-phosphate that binds to S1P1/EDG-1, S1P3/EDG-3, and S1P2/EDG-5 receptors with affinities of 115%, 83%, and 103%, respectively, relative to S1P in CHO... | |||
T74736 | 2MD | ||
2MD, an orally active vitamin D analog, both stimulates periosteal bone formation and decreases trabecular bone resorption, effectively restoring trabecular and cortical bone mass and strength. Additionally, 2MD regulate... | |||
T37952 | Sphinganine-1-phosphate (d17:0) | Sphinganine-1-phosphate (d17:0) | |
Sphinganine-1-phosphate (d17:0) is a sphingolipid analog of sphinganine-1-phosphate (d18:0) and sphingosine-1-phosphate (d18:1) that has a 17-carbon base. Sphinganine-1-phosphate (d17:0) levels are lower in surgical and ... | |||
T63637 | ROCK-IN-4 | ||
ROCK-IN-4 is a potent inhibitor of ROCK and maintains NO release capacity.ROCK-IN-4 reversibly depolymerizes F-actin and blocks mitochondrial respiration in human trabecular meshwork (HTM) cells.ROCK-IN-4 can be used to ... | |||
T70763 | KR-67607 | ||
KR-67607, also known as NTX-101 is novel selective 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1) inhibitor. KR-67607 decreased 4-hydroxynonenal expression and increased antioxidant and mucus secretion in BAC-treated rat ... | |||
T83848 | VnP-16 TFA | ||
VnP-16, a synthetic peptide fragment mirroring amino acids 270-281 of vitronectin (a multifunctional glycoprotein involved in cell attachment, migration, and spreading), promotes attachment and spreading of isolated huma... |