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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T8483 | Cysteine thiol probe | Methyl (4-bromobenzoyl)-L-cysteinate | Others |
Cysteine thiol probe (Methyl (4-bromobenzoyl)-L-cysteinate) is a chemoselective thiol probe for detection of electrophilic metabolites | |||
TQ0133 | Amifostine thiol dihydrochloride | WR 1065 | p53 |
Amifostine thiol dihydrochloride (WR 1065) can activate p53 through a JNK-dependent signaling pathway. It also protects normal tissues from the toxic effects of certain cancer drugs. | |||
T38701 | Thiol-C9-PEG4 | Thiol-C9-PEG4 | |
Thiol-C9-PEG4 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system wit... | |||
T38703 | Thiol-C9-PEG7 | Thiol-C9-PEG7 | |
Thiol-C9-PEG7 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system wit... | |||
T38702 | Thiol-C9-PEG5 | Thiol-C9-PEG5 | |
Thiol-C9-PEG5 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system wit... | |||
T40746 | M-PEG7-thiol | m-PEG7-thiol | |
m-PEG7-thiol is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system with... | |||
T38756 | Thiol-C10-amide-PEG8 | Thiol-C10-amide-PEG8 | |
Thiol-C10-amide-PEG8 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome sys... | |||
T40824 | Thiol-C9-PEG4-acid | Thiol-C9-PEG4-acid | |
Thiol-C9-PEG4-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome syste... | |||
T17078 | Thiol-PEG4-Boc | Thiol-PEG4-t-butyl ester | Others |
Thiol-PEG4-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system wi... | |||
T17075 | Thiol-PEG3-Boc | Thiol-PEG3-t-butyl ester | Others |
Thiol-PEG3-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system wi... | |||
T23728 | Aminooxy-PEG3-C2-thiol | Aminooxy-PEG3-thiol HCl,Aminooxy-PEG3-thiol HCl salt | |
Aminooxy-PEG3-thiol HCl salt is an Aminooxy PEG Linker. PEG Linkers may be useful in the development of antibody-drug conjugates and drug delivery methods. | |||
T34789 | Thiol-PEG3-NHBoc | t-Boc-N-amido-PEG3-thiol | |
t-Boc-N-amido-PEG3-thiol is a PEG derivative containing a Boc-protected amino group and a thiol group. | |||
T38821 | Thiol-PEG2-t-butyl ester | Thiol-PEG2-t-butyl ester | |
Thiol-PEG2-t-butyl ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome... | |||
T20973 | Thiol-C2-PEG2-OH | Thiol-PEG3-alcohol,HS-PEG3-OH | |
Thiol-PEG3-alcohol is a PEG derivative containing a hydroxyl group and a thiol group. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement wit... | |||
T37538 | Amifostine thiol | ||
Amifostine thiol (WR-1065), the active metabolite of cytoprotector Amifostine, serves as a cytoprotective agent possessing radioprotective properties. It activates p53 via a JNK-dependent signaling pathway[1][2][3]. | |||
T18184 | M-PEG3-SH | M-PEG3-Thiol,2-(2-(2-Methoxyethoxy)Ethoxy)Ethanethiol | Others , PROTAC Linker |
m-PEG3-SH (M-PEG3-Thiol) is a PEG-based PROTAC linker. m-PEG3-SH can be used in the synthesis of PROTACs. | |||
T12776L | Real Thiol | Others | |
Real Thiol, a reversible reaction-based fluorescent probe, can quantitatively monitor the real-time glutathione dynamics in living cells. | |||
T18600 | VH032 thiol | VHL ligand 6 | Others |
VH032 thiol (VHL ligand 6) is a VHL ligand that interacts with pan-BET inhibitor JQ1 through a linker to create a PROTAC[1] compound. | |||
T18842 | Thiol-PEG6-acid | Others | |
Thiol-PEG6-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system w... | |||
T30477 | Bis-PEG5-thiol | ||
Bis-PEG5-thiol is a PEG derivative containing two thiol groups. The thiol groups react with maleimide, OPSS, vinylsulfone and transition metal surfaces including gold, silver, etc. The hydrophilic PEG spacer increases so... |