Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Thiol-PEG4-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | 5 days | $ 43.00 | |
10 mg | 5 days | $ 61.00 |
Description | Thiol-PEG4-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Synonyms | Thiol-PEG4-t-butyl ester |
Molecular Weight | 338.46 |
Formula | C15H30O6S |
CAS No. | 564476-33-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Thiol-PEG4-Boc 564476-33-1 Others Thiol PEG4 Boc Thiol-PEG-4-Boc Thiol-PEG4-t-butyl ester ThiolPEG4Boc inhibitor inhibit