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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T29137 | VU0453595 | VU 0453595,VU-0453595 | AChR |
VU0453595 is a M1 positive allosteric modulator (PAM). | |||
T0281 | Meclocycline sulfosalicylate salt | Meclutin,Mecloderm,Meclan Cream | Antibacterial , Antibiotic |
Meclocycline sulfosalicylate salt (Mecloderm), a tetracycline antibiotic, is used topically (i.e. for skin infections) as it is totally insoluble in water and may damage kidney and liver if given systemically. | |||
T68060 | Elgodipine | ||
Elgodipine significantly reduced the incidence and severity of exercise-induced angina pectoris systemically and was able to inhibit vascular smooth muscle proliferation through a mechanism independent of the expression ... | |||
T27909 | LY 274614 | ||
LY 274614 is a structurally novel systemically active competitive NMDA receptor antagonist. | |||
T27680 | JNJ-40068782 | JNJ 40068782 | |
JNJ-40068782 is a potent, selective and systemically active positive allosteric modulator of the mGlu2 receptor. | |||
T70619 | LY2934747 | ||
LY2934747 is a novel, potent, and systemically bioavailable mGlu2/3 receptor agonist, exhibiting both antipsychotic and analgesic properties in vivo. | |||
T41184 | Clocinnamox mesylate | C-CAM,NIH 10443 | |
Clocinnamox mesylate is a systemically active, irreversibleμ-opioid receptor antagonist (apparent Kivalues are 0.7, 1.9 and 5.7 nM for mouseμ,δandκreceptors respectively). | |||
T27897 | LY 215490 | LY215490,LY-215490 | |
LY 215490 is a selective, competitive and systemically active antagonist of AMPA receptor. LY 215490 has neuroprotective effect against focal ischaemia in a model of permanent MCA occlusion in the rat. | |||
T71931 | Clencyclohexerol | ||
Clencyclohexerol is an analog of clenbuterol. β-Adrenoceptor agonists, including clenbuterol, modulate protein synthesis and degradation and have therapeutic potential in muscle wasting disorders. β-adrenoceptor agonists... | |||
T68321 | AS1940477 | ||
AS1940477 is p38 MAPK inhibitor. AS1940477 inhibited the enzymatic activity of recombinant p38α and β isoforms but showed no effect against other 100 protein kinases including p38γ and δ isoforms. In human peripheral blo... | |||
T36204 | Methylatropine (nitrate) | ||
Methylatropine is an antagonist of muscarinic acetylcholine receptors (IC50= <0.1 nM in a radioligand binding assay using isolated porcine brain membranes) and a derivative of atropine .1,2It reduces acetylcholine-induce... | |||
T38844 | MK-8245 Trifluoroacetate | ||
MK-8245 trifluoroacetate is a phenoxy piperidine isoxazole derivative functioning as a potent, liver-targeting stearoyl-CoA desaturase (SCD) inhibitor, demonstrating significant anti-diabetic and anti-dyslipidemic effect... |