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Search Results for " systemically "

12

Compounds

Cat No. Product Name Synonyms Targets
T29137 VU0453595 VU 0453595,VU-0453595 AChR
VU0453595 is a M1 positive allosteric modulator (PAM).
T0281 Meclocycline sulfosalicylate salt Meclutin,Mecloderm,Meclan Cream Antibacterial , Antibiotic
Meclocycline sulfosalicylate salt (Mecloderm), a tetracycline antibiotic, is used topically (i.e. for skin infections) as it is totally insoluble in water and may damage kidney and liver if given systemically.
T68060 Elgodipine
Elgodipine significantly reduced the incidence and severity of exercise-induced angina pectoris systemically and was able to inhibit vascular smooth muscle proliferation through a mechanism independent of the expression ...
T27909 LY 274614
LY 274614 is a structurally novel systemically active competitive NMDA receptor antagonist.
T27680 JNJ-40068782 JNJ 40068782
JNJ-40068782 is a potent, selective and systemically active positive allosteric modulator of the mGlu2 receptor.
T70619 LY2934747
LY2934747 is a novel, potent, and systemically bioavailable mGlu2/3 receptor agonist, exhibiting both antipsychotic and analgesic properties in vivo.
T41184 Clocinnamox mesylate C-CAM,NIH 10443
Clocinnamox mesylate is a systemically active, irreversibleμ-opioid receptor antagonist (apparent Kivalues are 0.7, 1.9 and 5.7 nM for mouseμ,δandκreceptors respectively).
T27897 LY 215490 LY215490,LY-215490
LY 215490 is a selective, competitive and systemically active antagonist of AMPA receptor. LY 215490 has neuroprotective effect against focal ischaemia in a model of permanent MCA occlusion in the rat.
T71931 Clencyclohexerol
Clencyclohexerol is an analog of clenbuterol. β-Adrenoceptor agonists, including clenbuterol, modulate protein synthesis and degradation and have therapeutic potential in muscle wasting disorders. β-adrenoceptor agonists...
T68321 AS1940477
AS1940477 is p38 MAPK inhibitor. AS1940477 inhibited the enzymatic activity of recombinant p38α and β isoforms but showed no effect against other 100 protein kinases including p38γ and δ isoforms. In human peripheral blo...
T36204 Methylatropine (nitrate)
Methylatropine is an antagonist of muscarinic acetylcholine receptors (IC50= <0.1 nM in a radioligand binding assay using isolated porcine brain membranes) and a derivative of atropine .1,2It reduces acetylcholine-induce...
T38844 MK-8245 Trifluoroacetate
MK-8245 trifluoroacetate is a phenoxy piperidine isoxazole derivative functioning as a potent, liver-targeting stearoyl-CoA desaturase (SCD) inhibitor, demonstrating significant anti-diabetic and anti-dyslipidemic effect...
TargetMol