sst5 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TP2207	Pasireotide Acetate		Somatostatin
	Pasireotide Acetate is a stable cyclohexapeptide somatostatin mimic		Somatostatin
T21944L	BIM 23056 Acetate	BIM 23056 Acetate (150155-61-6 Free base)	Others
	BIM 23056 Acetate is a potent and surmountable human recombinant sst5 receptor antagonist.		Others
TP1570L	Cortistatin-14 acetate	Cortistatin-14 acetate(186901-48-4 Free base)	Somatostatin
	Cortistatin-14 acetate, a neuropeptide have structural similarity to somatostatin-14, binds and exerts its function via the somatostatin receptors (sst1-sst5). Cortistatin-14 acetate shows anticonvulsive, neuroprotective...		Somatostatin
TP1346	CYN 154806 TFA	CYN 154806 TFA	Somatostatin
	CYN 154806 TFA is a cyclic octapeptide and an effective selective somatostatin sst2 receptor antagonist. For the recombinant sst2, sst1, sst3, sst4 and sst5 receptors, the pIC50 values are 8.58, 5.41, 6.07, 5.76 and 6.48...		Somatostatin
T39262L	BIM-23190 aceate		Somatostatin
	BIM-23190 aceate, a somatostatin analog, a selective agonist of SSTR2 and SSTR5. BIM-23190 can be used in cancer and acromegaly studies.		Somatostatin
T22907	L-817,818		Others
	somatostatin sst5 receptor agonist		Others
T75844	BIM-23056 TFA
	BIM 23056 TFA, a potent linear octapeptide antagonist of sst3 and sst5 somatostatin receptors, exhibits inhibition constants (K_i) of 10.8 for sst3 and 5.7 for sst5, according to reference [1].
TP2122	Seglitide
	Peptide agonist for sst2 and sst5 somatostatin receptors. IC50/Kd values (nM) at cloned human somatostatin receptors are: > 1000 (sst1), 0.2 - 1.5 (sst2), 27 - 36 (sst3), > 127 (sst4), and 0.06 - 23 (sst5).
T76034	Cortistatin-14 TFA
	Cortistatin-14 (TFA), a neuropeptide resembling somatostatin-14 in structure, operates through interaction with somatostatin receptors (sst1-sst5). This compound exhibits anticonvulsive and neuroprotective effects alongs...
T32511L	L-796,778 acetate	L-796,778 acetate(217480-25-6 Free base)	Somatostatin
	L-796,778 acetate is a slective somatostatin receptor agonist with IC50 of 24nM for sst3, for sst1, sst2, sst4 and sst5, IC50 is >1000nM.		Somatostatin
TP1877	CYN 154806
	CYN 154806 is a potent and selective somatostatin sst2 receptor antagonist, The pIC50 values are 8.58, 5.41, 6.07, 5.76 and 6.48 for human recombinant sst2, sst1, sst3, sst4 and sst5 receptors respectively.
TP2045	CH 275
	Potent somatostatin receptor 1 (sst1) agonist; displays selectivity for sst1 (IC50 values are 30.9 nM, 345 nM, > 1 μM, > 10 μM and > 10μM for human sst1, sst3, sst4, sst2 and sst5 respectively). Attenuates somatostatin r...
T76596	PRL 3195
	PRL 3195 is a somatostatin receptor antagonist, exhibiting K i values of 6, 17, 66, 1000, and 1000 nM for human somatostatin receptors sst 5 , sst 2 , sst 3 , sst 1 , and sst 4, respectively [1].
T11800	L-803087		Somatostatin
	L-803087 is a potent and selective agonist of the growth inhibitor sst4 receptor with a Ki value of 0.7 nM for sst4, which is more than 280-fold more selective than other growth inhibitory receptors.L-803087 induced AMPA...		Somatostatin
T76042	Angiopeptin TFA
	Angiopeptin TFA, a cyclic octapeptide analogue of somatostatin, acts as a partial agonist at sst 2/sst 5 receptors, exhibiting IC50 values of 0.26 nM and 6.92 nM, respectively. This compound effectively inhibits the rele...
T25087	Angiopeptin	D-Nal-cys-tyr-trp-lys-val-cys-thr-NH2,Bim 23014 C
	Angiopeptin is a synthetic octapeptide analog of somatostatin; suppresses accelerated transplant atherosclerosis in rabbit heart arteries.
T13811	Pasireotide ditrifluoroacetate	SOM230 ditrifluoroacetate,Pasireotide ditrifluoroacetate (396091-73-9 free base),Pasireotide TFA salt	Others
	Pasireotide is a stable cyclohexapeptide somatostatin mimic.		Others
T12369	Pasireotide pamoate	SOM230 pamoate	Others
	Pasireotide pamoate is a stable cyclohexapeptide somatostatin mimic. Pasireotide pamoate exhibits antisecretory, antiproliferative, and proapoptotic activity.		Others
T39207	L-803087 TFA
	L-803087 TFA is a highly potent and selective agonist of the somatostatin sst4 receptor, exhibiting a Ki value of 0.7 nM. It displays a remarkable selectivity, being over 280-fold more preferential for the sst4 receptor ...