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Angiopeptin

Catalog No. T25087 CAS 113294-82-9

Synonyms: D-Nal-cys-tyr-trp-lys-val-cys-thr-NH2, Bim 23014 C

Angiopeptin is a synthetic octapeptide analog of somatostatin; suppresses accelerated transplant atherosclerosis in rabbit heart arteries.

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Angiopeptin, CAS 113294-82-9

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Biological Description

Chemical Properties

Storage & Solubility Information

Description	Angiopeptin is a synthetic octapeptide analog of somatostatin; suppresses accelerated transplant atherosclerosis in rabbit heart arteries.
Targets&IC50	SST2:0.26 nM (IC50), SST5:6.92 nM (IC50)

Synonyms	D-Nal-cys-tyr-trp-lys-val-cys-thr-NH2, Bim 23014 C
Molecular Weight	1098.34
Formula	C54H71N11O10S2
CAS No.	113294-82-9

Storage

keep away from moisture

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Meiser BM, Mueller M, Foegh M, Von Scheidt W, Reichart B. Short-term angiopeptin therapy and the incidence of graft vessel disease after heart transplantation. J Heart Lung Transplant. 2002 Dec;21(12):1264-73. PubMed PMID: 12490271. 2. Kwok OH, Chow WH, Law TC, Chiu A, Ng W, Lam WF, Hong MK, Popma JJ. First human experience with angiopeptin-eluting stent: a quantitative coronary angiography and three-dimensional intravascular ultrasound study. Catheter Cardiovasc Interv. 2005 Dec;66(4):541-6. PubMed PMID: 16208695. 3. Armstrong J, Gunn J, Arnold N, Malik N, Chan KH, Vick T, Stratford P, Cumberland DC, Holt CM. Angiopeptin-eluting stents: observations in human vessels and pig coronary arteries. J Invasive Cardiol. 2002 May;14(5):230-8. PubMed PMID: 11983942. 4. Sidney EJ, Hampl V, Nelson DP, Archer SL, Foegh ML, Cathapermal SS, Weir EK. The somatostatin analog angiopeptin does not reduce chronic hypoxic pulmonary hypertension in rats. Proc Soc Exp Biol Med. 1996 Oct;213(1):43-9. PubMed PMID: 8820822.

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Keywords

Angiopeptin 113294-82-9 D-Nal-cys-tyr-trp-lys-val-cys-thr-NH2 Bim 23014 C inhibitor inhibit

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